School of Cyberspace Science, Dongguan University of Technology, Dongguan, China.
Biotechnol Genet Eng Rev. 2024 Nov;40(3):2577-2596. doi: 10.1080/02648725.2023.2200333. Epub 2023 Apr 11.
The progressive loss of motor function in the brain is a hallmark of Parkinson's disease (PD). Electroencephalogram (EEG) signals are commonly used for early diagnosis since they are associated with a brain disorder. This work aims to find a better way to represent electroencephalography (EEG) signals and enhance the classification accuracy of individuals with Parkinson's disease using EEG signals. In this paper, we present two hybrid deep neural networks (DNN) that combine convolutional neural networks with long short-term memory to diagnose Parkinson's disease using EEG signals, that is, through the establishment of parallel and series combined models. The deep CNN network is utilized to acquire the structural features of ECG signals and extract meaningful information from them, after which the signals are sent via a long short-term memory network to extract the features' context dependency. The proposed architecture was able to achieve 97.6% specificity, 97.1% sensitivity, and 98.6% accuracy for a parallel model and 99.1% specificity, 98.5% sensitivity, and 99.7% accuracy for a series model, both in 3-class classification (PD patients with medication, PD patients without medication and healthy).
大脑运动功能的逐渐丧失是帕金森病(PD)的一个标志。脑电图(EEG)信号通常用于早期诊断,因为它们与大脑紊乱有关。这项工作旨在寻找一种更好的方法来表示脑电图(EEG)信号,并使用 EEG 信号提高帕金森病患者的分类准确性。在本文中,我们提出了两种混合深度神经网络(DNN),它们将卷积神经网络与长短时记忆相结合,使用 EEG 信号诊断帕金森病,即通过建立并行和串联组合模型。深度 CNN 网络用于获取 ECG 信号的结构特征,并从中提取有意义的信息,然后通过长短期记忆网络发送信号,以提取特征的上下文相关性。所提出的架构在 3 类分类(服用药物的 PD 患者、未服用药物的 PD 患者和健康人)中,对于并行模型,特异性为 97.6%,敏感性为 97.1%,准确性为 98.6%;对于串联模型,特异性为 99.1%,敏感性为 98.5%,准确性为 99.7%。