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3D 打印手术器械的快速低温灭菌在艰苦环境中的应用。

Rapid cold sterilization of 3D printed surgical instruments for the austere environment.

机构信息

Madigan Army Medical Center, 9040A Jackson Ave, Tacoma, WA, 98431, USA.

Madigan Army Medical Center, 9040A Jackson Ave, Tacoma, WA, 98431, USA.

出版信息

Am J Surg. 2023 May;225(5):909-914. doi: 10.1016/j.amjsurg.2023.03.010. Epub 2023 Mar 17.

DOI:10.1016/j.amjsurg.2023.03.010
PMID:37059641
Abstract

INTRODUCTION

Medical operations are vulnerable to global supply chain fluctuations. The ability to locally produce and reliably sterilize medical equipment may mitigate this risk. This project developed a reliable high-level disinfection process for 3D printed surgical tools.

METHODS

Surgical instruments and consumables were designed and printed from various materials. Devices contaminated with known and unknown bacteria underwent one of three cleaning methods followed by high-level disinfection using submersion in a Cidex OPA Solution. Devices were then cultured on blood agar plates and incubated for 48 h. Positive and negative controls were performed.

RESULTS

The results of control experiments showed no growth on negative controls and significant growth on all positive control plates. Of the three cleaning methods tested, one showed no growth: cleaning with isopropyl alcohol and chlorhexidine followed by Cidex bath.

DISCUSSION

This project successfully developed a rapid high-level disinfection process for 3D printed surgical instruments made from two different types of 3D printing material.

摘要

简介

医疗操作容易受到全球供应链波动的影响。能够在本地生产和可靠地对医疗设备进行消毒可能会降低这种风险。本项目开发了一种可靠的 3D 打印手术工具的高水平消毒工艺。

方法

设计并打印了各种材料的手术器械和耗材。用已知和未知细菌污染的器械,采用三种清洗方法中的一种,然后浸入 Cidex OPA 溶液中进行高水平消毒。然后将器械接种在血琼脂平板上,孵育 48 小时。进行阳性和阴性对照。

结果

对照实验的结果显示阴性对照无生长,所有阳性对照平板均有明显生长。在测试的三种清洗方法中,有一种方法显示无生长:异丙醇和洗必泰清洗后再用 Cidex 浴。

讨论

本项目成功开发了一种快速的 3D 打印手术器械的高水平消毒工艺,这些器械由两种不同类型的 3D 打印材料制成。

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