热带地区三倍体利什曼原虫的基因组分析。

Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics.

出版信息

Emerg Infect Dis. 2023 May;29(5):1076-1078. doi: 10.3201/eid2905.221456.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10124652/

Abstract

We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.

摘要

我们在哥斯达黎加发现了一种与巴拿马的杂交寄生虫在基因上相似的混合利什曼原虫。基因组分析表明，这种杂交种是三倍体，并确定了与 L. braziliensis 和 L. guyanensis 相关的菌株为亲本。我们的研究结果强调了存在人类感染的采样不足的利什曼原虫（Viannia）变体。