新型抗生素纳吡霉素。生产、分离、理化性质及生物活性。
Novel antibiotics napyradiomycins. Production, isolation, physico-chemical properties and biological activity.
作者信息
Shiomi K, Iinuma H, Hamada M, Naganawa H, Manabe M, Matsuki C, Takeuchi T, Umezawa H
出版信息
J Antibiot (Tokyo). 1986 Apr;39(4):487-93. doi: 10.7164/antibiotics.39.487.
PMID:3710909
Abstract
Novel antibacterial antibiotics napyradiomycins A, B1, B2, B3, C1 and C2 have been isolated from the culture broth of Chainia rubra MG802-AF1. In this paper, taxonomy of the producer, and production, isolation, physico-chemical properties and biological activities of napyradiomycins are reported. They contain the naphtopyran chromophore and halogens, and inhibit the growth of Gram-positive bacteria including drug-resistant strains.
摘要
新型抗菌抗生素萘并放线菌素A、B1、B2、B3、C1和C2已从红色链霉菌MG802-AF1的培养液中分离出来。本文报道了其产生菌的分类学，以及萘并放线菌素的生产、分离、理化性质和生物活性。它们含有萘并吡喃发色团和卤素，可抑制包括耐药菌株在内的革兰氏阳性菌的生长。
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