Division of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN, USA.
Womens Health (Lond). 2023 Jan-Dec;19:17455057231170975. doi: 10.1177/17455057231170975.
Cotesting with the Papanicolaou (Pap) and human papillomavirus tests detects most precancerous and cancerous lesions and increases the sensitivity for detecting high-grade precancerous and invasive cervical cancers compared with human papillomavirus testing alone.
To compare the use of the Papette brush (hereafter Papette) to the traditional spatula with endocervical brush (cytobrush) for cervical cancer screening.
Pragmatic observational study.
Adult women aged 21-64 years who were eligible for a Papanicolaou test at a Midwest Community Internal Medicine practice underwent cervical cancer screening using the Papette or spatula with cytobrush from 18 August 2021 through 1 February 2022. Cluster sampling was used across the practice. Pathology reports were then analyzed to compare the number of satisfactory versus unsatisfactory results between the two collection techniques.
We collected results for 756 Pap tests. The test results were satisfactory with the Papette 93.8% of the time compared with 93.0% for the spatula with cytobrush.
The Papette is not inferior to a spatula with cytobrush as a collection method for Pap tests.
巴氏涂片（Pap）和人乳头瘤病毒（HPV）联合检测可检测出大多数癌前病变和癌症，并提高了对高级别癌前病变和浸润性宫颈癌的检测灵敏度，比单独进行 HPV 检测效果更好。
比较巴氏涂片细胞学采样器（Papette）和传统宫颈刷（ cytobrush）用于宫颈癌筛查的效果。
实用观察性研究。
2021 年 8 月 18 日至 2022 年 2 月 1 日期间，在中西部社区内科执业处，年龄在 21-64 岁之间且符合巴氏涂片检测条件的成年女性，使用 Papette 或传统宫颈刷（ cytobrush）进行宫颈癌筛查。采用整群抽样方法在整个实践中进行。然后对病理报告进行分析，比较两种采集技术的满意结果和不满意结果的数量。
我们共收集了 756 份巴氏涂片检测结果。使用 Papette 时，检测结果满意的比例为 93.8%，而使用传统宫颈刷（ cytobrush）时，检测结果满意的比例为 93.0%。
Papette 作为巴氏涂片检测的采集方法并不逊于传统宫颈刷（ cytobrush）。
