Matthysse S, Holzman P S, Lange K
J Psychiatr Res. 1986;20(1):57-67. doi: 10.1016/0022-3956(86)90023-3.
The first-degree relatives of probands with schizophrenia tend to have abnormal smooth pursuit eye tracking, even when the proband's smooth pursuit is normal. In order to account for this finding, we propose that schizophrenia and disturbed eye tracking are independent expressions of an underlying "latent" trait which is genetically transmitted. The data on manic-depressive illness, but not schizophrenia, fit a simpler model in which abnormal smooth pursuit is a consequence of the psychiatric illness, rather than an independent expression of an underlying trait.
精神分裂症先证者的一级亲属往往存在异常的平稳跟踪眼球运动，即使先证者的平稳跟踪正常。为了解释这一发现，我们提出精神分裂症和紊乱的眼球运动是一种潜在的“隐性”特质的独立表现，这种特质是通过基因传递的。关于躁郁症而非精神分裂症的数据符合一个更简单的模型，即异常的平稳跟踪是精神疾病的结果，而非潜在特质的独立表现。
