Guo Mengqing, Shen Qian, Wu Yu, Li Lili, Zhang Lin, Wang Yu, Zhang Yanjun, Zhuang Pengwei, Guo Hong
State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617 China.
Chinese Materia Medica College, Haihe Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617 China.
Food Sci Biotechnol. 2023 Jan 21;32(7):911-920. doi: 10.1007/s10068-022-01229-2. eCollection 2023 Jun.
Ginger () is one of the most widely consumed dietary supplements. However, the content of active ingredients varied greatly from place to place. In this study, we first identified and compared the compositions of ginger samples from six different origins. Then, we evaluated the anti-inflammatory activity of different samples in LPS-stimulated RAW264.7 cells. The results indicated that highly variable in chemical composition and activity for ginger from different origin. Further, correlation analysis showed that isoborneol, terpineol, α-curcumene, germacrene D, α-elemol and 8-shogaol exhibited a strong correlation with inflammatory factors, which could be used as potential chemical markers to evaluate quality and distinguish source of ginger. Finally, comprehensive evaluation found that the ginger from Sichuan exerts stronger anti-inflammatory properties. This study will help to select ginger varieties with excellent characteristics, provide theoretical basis for the development and utilization of ginger.
The online version contains supplementary material available at 10.1007/s10068-022-01229-2.
生姜是最广泛食用的膳食补充剂之一。然而，其活性成分的含量因产地不同而有很大差异。在本研究中，我们首先鉴定并比较了来自六个不同产地的生姜样品的成分。然后，我们评估了不同样品在脂多糖刺激的RAW264,7细胞中的抗炎活性。结果表明，不同产地生姜的化学成分和活性差异很大。此外，相关性分析表明，异龙脑、萜品醇、α-姜黄烯、吉马烯D、α-榄香烯和8-姜辣素与炎症因子呈强相关，可作为评估生姜质量和区分生姜来源的潜在化学标志物。最后，综合评价发现四川生姜具有更强的抗炎特性。本研究将有助于筛选优良特性的生姜品种，为生姜的开发利用提供理论依据。
在线版本包含可在10.1007/s10068-022-01229-2获取的补充材料。
