• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

退行性系统性硬化症

Regressive systemic sclerosis.

作者信息

Black C, Dieppe P, Huskisson T, Hart F D

出版信息

Ann Rheum Dis. 1986 May;45(5):384-8. doi: 10.1136/ard.45.5.384.

DOI:10.1136/ard.45.5.384
PMID:3718012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1001896/
Abstract

Systemic sclerosis is a disease which usually progresses or reaches a plateau with persistence of symptoms and signs. Regression is extremely unusual. Four cases of established scleroderma are described in which regression is well documented. The significance of this observation and possible mechanisms of disease regression are discussed.

摘要

系统性硬化症是一种通常会持续发展或症状体征持续存在并达到平台期的疾病。病情缓解极为罕见。本文描述了4例确诊硬皮病患者病情缓解且有充分记录的情况。文中讨论了这一观察结果的意义以及疾病缓解的可能机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398b/1001896/26e12bad8d3f/annrheumd00272-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398b/1001896/73954818934f/annrheumd00272-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398b/1001896/26e12bad8d3f/annrheumd00272-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398b/1001896/73954818934f/annrheumd00272-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/398b/1001896/26e12bad8d3f/annrheumd00272-0033-b.jpg

相似文献

1
Regressive systemic sclerosis.退行性系统性硬化症
Ann Rheum Dis. 1986 May;45(5):384-8. doi: 10.1136/ard.45.5.384.
2
Scleroderma (progressive systemic sclerosis): progress and course based on a personal series of 118 cases.硬皮病（进行性系统性硬化症）：基于118例个人病例的进展与病程
Med J Aust. 1978 Aug 12;2(4):129-34. doi: 10.5694/j.1326-5377.1978.tb131413.x.
3
[Systemic sclerosis (scleroderma) without scleroderma].[无硬皮病的系统性硬化症（硬皮病）]
Lik Sprava. 2001 May-Jun(3):93-4.
4
Capillary abnormalities, Raynaud's phenomenon, and systemic sclerosis in patients with localized scleroderma.局限性硬皮病患者的毛细血管异常、雷诺现象和系统性硬化症。
Arch Dermatol. 1992 May;128(5):630-2.
5
Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: association of interleukin 12 elevation with spontaneous regression of skin sclerosis.系统性硬化症患者血清细胞因子浓度的纵向分析：白细胞介素12升高与皮肤硬化自发消退的关联
J Rheumatol. 2006 Feb;33(2):275-84.
6
Predictors of the scleroderma phenotype in fibroblasts from systemic sclerosis patients.
J Eur Acad Dermatol Venereol. 2009 Feb;23(2):160-8. doi: 10.1111/j.1468-3083.2008.03016.x. Epub 2008 Nov 27.
7
Nodular (keloidal) scleroderma.
J Am Acad Dermatol. 1984 Dec;11(6):1111-4. doi: 10.1016/s0190-9622(84)70268-4.
8
Systemic Sclerosis Sine Scleroderma in Mexican Patients. Case Reports.墨西哥患者的无硬皮病系统性硬化症。病例报告。
Reumatol Clin (Engl Ed). 2018 Jul-Aug;14(4):230-232. doi: 10.1016/j.reuma.2016.11.004. Epub 2017 Jan 3.
9
Systemic sclerosis sine scleroderma: an unusual presentation in scleroderma renal crisis.无硬皮病的系统性硬化症：硬皮病肾危象中的一种不寻常表现。
J Rheumatol. 1995 Mar;22(3):557-60.
10
Assessment of esophageal involvement in systemic sclerosis and morphea (localized scleroderma) by clinical, endoscopic, manometric and pH metric features: a prospective comparative hospital based study.通过临床、内镜、测压和pH值测量特征评估系统性硬化症和硬斑病（局限性硬皮病）中的食管受累情况：一项基于医院的前瞻性对照研究。
BMC Gastroenterol. 2015 Feb 15;15:24. doi: 10.1186/s12876-015-0241-2.

引用本文的文献

1
Efficacy of Mycophenolate Mofetil in Treating Skin Fibrosis in Systemic Sclerosis: A Systematic Review and Meta-Analysis.霉酚酸酯治疗系统性硬化症皮肤纤维化的疗效：一项系统评价和荟萃分析。
J Clin Med. 2025 Jun 12;14(12):4187. doi: 10.3390/jcm14124187.
2
Calcineurin inhibitors in systemic sclerosis - a systematic literature review.系统性硬化症中的钙调神经磷酸酶抑制剂——一项系统文献综述
Ther Adv Musculoskelet Dis. 2022 May 19;14:1759720X221092374. doi: 10.1177/1759720X221092374. eCollection 2022.

本文引用的文献

1
Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.系统性硬化症（硬皮病）分类的初步标准。美国风湿病协会诊断与治疗标准委员会硬皮病标准小组委员会。
Arthritis Rheum. 1980 May;23(5):581-90. doi: 10.1002/art.1780230510.
2
Increased frequency of HLA-DR5 in scleroderma.硬皮病中HLA - DR5频率增加。
Arthritis Rheum. 1981 Jun;24(6):854-6. doi: 10.1002/art.1780240614.
3
Increased frequency of B8/DR3 in scleroderma and association of the haplotype with impaired cellular immune response.
硬皮病中B8/DR3频率增加及该单倍型与细胞免疫反应受损的关联。
Clin Exp Immunol. 1981 Mar;43(3):478-85.
4
HLA antigens, autoantibodies and clinical subsets in scleroderma.硬皮病中的人类白细胞抗原、自身抗体及临床亚组
Br J Rheumatol. 1984 Nov;23(4):267-71. doi: 10.1093/rheumatology/23.4.267.
5
Diversity of antinuclear antibodies in progressive systemic sclerosis. Anti-centromere antibody and its relationship to CREST syndrome.进行性系统性硬化症中抗核抗体的多样性。抗着丝点抗体及其与CREST综合征的关系。
Arthritis Rheum. 1980 Jun;23(6):617-25. doi: 10.1002/art.1780230602.
6
Genetic susceptibility to scleroderma-like syndrome induced by vinyl chloride.
Lancet. 1983 Jan 1;1(8314-5):53-5. doi: 10.1016/s0140-6736(83)91578-7.
7
Biosynthesis and maturation of skin collagen in scleroderma, and effect of D-penicillamine.
Lancet. 1974 Feb 9;1(7850):187-92. doi: 10.1016/s0140-6736(74)92494-5.
8
Survival with systemic sclerosis (scleroderma). A life-table analysis of clinical and demographic factors in 309 patients.
Ann Intern Med. 1971 Sep;75(3):369-76. doi: 10.7326/0003-4819-75-3-369.
9
Pathogenesis of systemic sclerosis: a vascular hypothesis.系统性硬化症的发病机制：一种血管假说。
Semin Arthritis Rheum. 1975 May;4(4):351-68. doi: 10.1016/0049-0172(75)90017-7.
10
Immunological mechanisms in the pathogenesis of vinyl chloride disease.氯乙烯病发病机制中的免疫机制。
Br Med J. 1976 Apr 17;1(6015):936-8. doi: 10.1136/bmj.1.6015.936.