Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Huddinge, Sweden.
J Exp Med. 2023 Jul 3;220(7). doi: 10.1084/jem.20230550. Epub 2023 May 15.
The oral mucosa serves as a frontline defense against many infections. Stolley et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20221853) discovered that the oral mucosa houses CD8+ CD103+ resident memory T cells, which are important for protecting against local viral infections in mice.
口腔黏膜是抵御许多感染的第一道防线。Stolley 等人(2023. J. Exp. Med.https://doi.org/10.1084/jem.20221853)发现,口腔黏膜中存在 CD8+ CD103+ 常驻记忆 T 细胞,这些细胞对于保护小鼠免受局部病毒感染非常重要。