克罗恩病、溃疡性结肠炎和乳糜泻患者体内的玉米抗体。
Antibodies to maize in patients with Crohn's disease, ulcerative colitis and coeliac disease.
作者信息
Davidson I W, Lloyd R S, Whorwell P J, Wright R
出版信息
Clin Exp Immunol. 1979 Jan;35(1):147-8.
Abstract
The incidence of antibodies to maize using an immunofluorescent technique has been found to be 14% in controls, 33% in Crohn's disease, 50% in ulcerative colitis and 44% in coeliac disease. This result indicates that humoral immunity to maize is probably unimportant in the pathogenesis of Crohn's disease. The similar incidence of antibodies in the inflammatory bowel disease and coeliac groups suggests absorption of dietary antigen secondary to an increased mucosal permeability.
摘要
采用免疫荧光技术检测发现，对照组中玉米抗体的发生率为14%，克罗恩病患者中为33%，溃疡性结肠炎患者中为50%，乳糜泻患者中为44%。这一结果表明，针对玉米的体液免疫在克罗恩病的发病机制中可能并不重要。炎症性肠病组和乳糜泻组中抗体发生率相似，提示饮食抗原的吸收是黏膜通透性增加的继发结果。
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