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基于纳米技术的冠状病毒诊断生物传感器的最新进展

Recent Developments in Nanotechnology-Based Biosensors for the Diagnosis of Coronavirus.

作者信息

Yadav Sarita K, Yadav Rahul Deo, Tabassum Heena, Arya Malti

机构信息

Department of Pharmacy, MLN Medical College, Prayagraj, Uttar Pradesh India.

Dr. D. Y. Patil Biotechnology and Bioinformatics Institute, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra India.

出版信息

Plasmonics. 2023;18(3):955-969. doi: 10.1007/s11468-023-01822-z. Epub 2023 Mar 27.

DOI:10.1007/s11468-023-01822-z
PMID:37229148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10040920/
Abstract

The major challenge in today's world is that medical research is facing the existence of a vast number of viruses and their mutations, which from time to time cause outbreaks. Also, the continuous and spontaneous mutations occurring in the viruses and the emergence of resistant virus strains have become serious medical hazards. So, in view of the growing number of diseases, like the recent COVID-19 pandemic that has caused the deaths of millions of people, there is a need to improve rapid and sensitive diagnostic strategies to initiate timely treatment for such conditions. In the cases like COVID-19, where a real cure due to erratic and ambiguous signs is not available, early intervention can be life-saving. In the biomedical and pharmaceutical industries, nanotechnology has evolved exponentially and can overcome multiple obstacles in the treatment and diagnosis of diseases. Nanotechnology has developed exponentially in the biomedical and pharmaceutical fields and can overcome numerous challenges in the treatment and diagnosis of diseases. At the nano stage, the molecular properties of materials such as gold, silver, carbon, silica, and polymers get altered and can be used for the creation of reliable and accurate diagnostic techniques. This review provides insight into numerous diagnostic approaches focused on nanoparticles that could have been established for quick and early detection of such diseases.

摘要

当今世界面临的主要挑战是医学研究正面对大量病毒及其突变的存在,这些病毒不时引发疫情。此外,病毒持续自发的突变以及耐药病毒株的出现已成为严重的医学危害。所以,鉴于疾病数量不断增加,比如近期导致数百万人死亡的新冠疫情,有必要改进快速且灵敏的诊断策略,以便针对此类病症及时展开治疗。在像新冠疫情这样因症状不稳定且不明确而尚无真正治愈方法的情况下,早期干预可能挽救生命。在生物医学和制药行业,纳米技术呈指数级发展,能够克服疾病治疗和诊断中的多重障碍。纳米技术在生物医学和制药领域呈指数级发展,能够克服疾病治疗和诊断中的众多挑战。在纳米阶段,金、银、碳、二氧化硅和聚合物等材料的分子特性会发生改变,可用于创建可靠且准确诊断技术。本综述深入探讨了众多聚焦于纳米颗粒的诊断方法,这些方法可用于快速早期检测此类疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/10040920/2861138e79c3/11468_2023_1822_Fig5_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/10040920/c6d05ac1de1e/11468_2023_1822_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/10040920/3529ac351898/11468_2023_1822_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/10040920/62f74c2a19ff/11468_2023_1822_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371c/10040920/c24a5aeec627/11468_2023_1822_Fig4_HTML.jpg
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