Almawgani Abdulkarem H M, Awasthi Suneet Kumar, Mehaney Ahmed, Ali Ghassan Ahmed, Elsayed Hussein A, Sayed Hassan, Ahmed Ashour M
Electrical Engineering Department, College of Engineering, Najran University Najran Kingdom of Saudi Arabia.
Department of Physics and Material Science and Engineering, Jaypee Institute of Information Technology Noida 201304 U.P. India.
RSC Adv. 2023 May 30;13(24):16154-16164. doi: 10.1039/d3ra01984e.
In this study, the biosensing capabilities of conventional and hybrid multilayer structures were theoretically examined based on surface plasmon resonance (SPR). The transfer matrix method is adopted to obtain the reflectance spectra of the hybrid multilayer structure in the visible region. In this regard, the considered SPR sensor is configured as, [prism (CaF)/AlO/Ag/AlO/2D material/AlO/Sensing medium]. Interestingly, many optimization steps were conducted to obtain the highest sensitivity of the new SPR biosensor from the hybrid structure. Firstly, the thickness of an AlO layer with a 2D material (Blue P/WS) is optimized to obtain an upgraded sensitivity of 360° RIU. Secondly, the method to find the most appropriate 2D material for the proposed design is investigated to obtain an ultra-high sensitivity. Meanwhile, the inclusion of black phosphorus (BP) increases the sensor's sensitivity to 466° RIU. Thus, black phosphorus (BP) was obtained as the most suitable 2D material for the proposed design. In this regard, the proposed hybrid SPR biosensing design may pave the way for further opportunities for the development of various SPR sensors to be utilized in chemical and biomedical engineering fields.
在本研究中，基于表面等离子体共振（SPR）从理论上研究了传统多层结构和混合多层结构的生物传感能力。采用转移矩阵法来获取混合多层结构在可见光区域的反射光谱。在此方面，所考虑的SPR传感器配置为[棱镜（CaF）/AlO/Ag/AlO/二维材料/AlO/传感介质]。有趣的是，进行了许多优化步骤以从混合结构中获得新型SPR生物传感器的最高灵敏度。首先，对带有二维材料（蓝磷/WS）的AlO层的厚度进行优化，以获得360°/RIU的提升灵敏度。其次，研究了为所提出的设计找到最合适二维材料的方法以获得超高灵敏度。同时，加入黑磷（BP）可将传感器的灵敏度提高到466°/RIU。因此，黑磷（BP）被确定为所提出设计中最合适的二维材料。在这方面，所提出的混合SPR生物传感设计可能为在化学和生物医学工程领域中开发各种SPR传感器的进一步发展机会铺平道路。
