Institute of Physical Chemistry, College of Chemistry, Jilin University, 2519 Jiefang Road, Changchun 130021, PR China.
Institute of Physical Chemistry, College of Chemistry, Jilin University, 2519 Jiefang Road, Changchun 130021, PR China.
Food Chem. 2023 Nov 1;425:136518. doi: 10.1016/j.foodchem.2023.136518. Epub 2023 Jun 3.
Electrochemical sensors and biosensors play an important role in many fields, including biology, clinical trials, and food industry. For health and food safety monitoring, accurate and quantitative sensing is needed to ensure that there is no significantly negative impact on human health. It is difficult for traditional sensors to meet these requirements. In recent years, single-atom nanozymes (SANs) have been successfully used in electrochemical sensors due to their high electrochemical activity, good stability, excellent selectivity and high sensitivity. Here, we first summarize the detection principle of SAN-based electrochemical sensors. Then, we review the detection performances of small molecules on SAN-based electrochemical sensors, including HO, dopamine (DA), uric acid (UA), glucose, HS, NO, and O. Subsequently, we put forward the optimization strategies to promote the development of SAN-based electrochemical sensors. Finally, the challenges and prospects of SAN-based sensors are proposed.
电化学传感器和生物传感器在许多领域发挥着重要作用，包括生物学、临床试验和食品工业。为了进行健康和食品安全监测，需要进行准确和定量的传感，以确保对人体健康没有显著的负面影响。传统传感器很难满足这些要求。近年来，由于单原子纳米酶（SANs）具有高电化学活性、良好的稳定性、优异的选择性和高灵敏度，已成功应用于电化学传感器中。在这里，我们首先总结了基于 SAN 的电化学传感器的检测原理。然后，我们回顾了基于 SAN 的电化学传感器对小分子的检测性能，包括 HO、多巴胺（DA）、尿酸（UA）、葡萄糖、HS、NO 和 O。随后，我们提出了促进基于 SAN 的电化学传感器发展的优化策略。最后，提出了基于 SAN 的传感器的挑战和前景。
