Jeyachandran Sivakamavalli, Srinivasan Ramachandran, Ramesh Thiyagarajan, Parivallal Arumugam, Lee Jintae, Sathiyamoorthi Ezhaveni
Laboratory in Biotechnology & Biosignal Transduction, Department of Orthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, Tamil Nadu, India.
Centre for Ocean Research (DST-FIST Sponsored Centre), MoES-Earth Science and Technology Cell (Marine Biotechnological Studies), Sathyabama Research Park, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India.
Biomimetics (Basel). 2023 Sep 21;8(5):446. doi: 10.3390/biomimetics8050446.
Nanozymes represent a category of nano-biomaterial artificial enzymes distinguished by their remarkable catalytic potency, stability, cost-effectiveness, biocompatibility, and degradability. These attributes position them as premier biomaterials with extensive applicability across medical, industrial, technological, and biological domains. Following the discovery of ferromagnetic nanoparticles with peroxidase-mimicking capabilities, extensive research endeavors have been dedicated to advancing nanozyme utilization. Their capacity to emulate the functions of natural enzymes has captivated researchers, prompting in-depth investigations into their attributes and potential applications. This exploration has yielded insights and innovations in various areas, including detection mechanisms, biosensing techniques, and device development. Nanozymes exhibit diverse compositions, sizes, and forms, resembling molecular entities such as proteins and tissue-based glucose. Their rapid impact on the body necessitates a comprehensive understanding of their intricate interplay. As each day witnesses the emergence of novel methodologies and technologies, the integration of nanozymes continues to surge, promising enhanced comprehension in the times ahead. This review centers on the expansive deployment and advancement of nanozyme materials, encompassing biomedical, biotechnological, and environmental contexts.
纳米酶是一类纳米生物材料人工酶，其特点是具有卓越的催化效力、稳定性、成本效益、生物相容性和可降解性。这些特性使其成为在医学、工业、技术和生物领域具有广泛适用性的优质生物材料。在发现具有过氧化物酶模拟能力的铁磁性纳米颗粒之后，大量研究致力于推动纳米酶的应用。它们模拟天然酶功能的能力吸引了研究人员，促使他们深入研究其特性和潜在应用。这一探索在检测机制、生物传感技术和设备开发等各个领域都产生了见解和创新。纳米酶呈现出多样的组成、尺寸和形态，类似于蛋白质和基于组织的葡萄糖等分子实体。它们对身体的快速影响需要全面了解其复杂的相互作用。随着每天都有新方法和新技术出现，纳米酶的整合持续激增，有望在未来增进理解。本综述聚焦于纳米酶材料在生物医学、生物技术和环境背景下的广泛应用与进展。
