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从孟加拉国视角看,制定针对尼帕病毒的预防措施和治疗策略是当务之急。

Development of Preventive Measures and Treatment Strategies Against Nipah Virus is a Timely Need: Bangladeshi Perspective.

作者信息

Urmi Taslima Jamal, Dewan Syed Masudur Rahman, Rahman Jannatul Mabia, Sharmin Syeda Nusrat, Hassan Md Mahadi

机构信息

Department of Pharmacy, School of Medicine, University of Asia Pacific, Dhaka, Bangladesh.

Department of Electrical and Electronic Engineering, University of Asia Pacific, Dhaka, Bangladesh.

出版信息

Clin Pathol. 2023 Jun 20;16:2632010X231183314. doi: 10.1177/2632010X231183314. eCollection 2023 Jan-Dec.

Abstract

Viral epidemics of variable frequency and severity have wreaked havoc and panic across the world. The Nipah virus (NiV), which has been linked to multiple outbreaks, mostly in South and Southeast Asia, is regarded as one of the deadliest in the world. In Bangladesh, seasonal outbreaks of encephalitis caused by the NiV have occurred annually since 2003. In particular, NiV has numerous characteristics that highlight its potential as a pandemic danger, such as its human-to-human transmission capability and its propensity to infect humans directly from natural reservoirs and/or from other animals. Numerous types of research investigate the pathophysiology and viral mechanisms of disease progression. The NiV and its disease have been studied thoroughly but attempts to implement preventive techniques have met cultural and social obstacles. This review highlights the NiV outbreaks, and its present status, the preventative and control measures implemented, the potential causes of the outbreaks in Bangladesh, and the precautions that must be taken by both government and nongovernment entities to contain the outbreaks and assure a future with fewer or no occurrences.

摘要

频率和严重程度各异的病毒流行在全球范围内造成了严重破坏和恐慌。尼帕病毒(NiV)与多次疫情爆发有关,主要发生在南亚和东南亚,被视为世界上最致命的病毒之一。自2003年以来,在孟加拉国每年都会发生由尼帕病毒引起的季节性脑炎疫情。特别是,尼帕病毒具有许多特征,凸显了其作为大流行危险的潜力,例如其人际传播能力以及直接从天然宿主和/或其他动物感染人类的倾向。众多类型的研究探讨了疾病进展的病理生理学和病毒机制。对尼帕病毒及其所致疾病已进行了深入研究,但实施预防技术的尝试遇到了文化和社会障碍。本综述重点介绍了尼帕病毒疫情及其现状、实施的预防和控制措施、孟加拉国疫情爆发的潜在原因,以及政府和非政府实体为控制疫情并确保未来疫情较少发生或不再发生而必须采取的预防措施。

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本文引用的文献

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