Yu Kan, Zhang Qinrou, Dai Zixiang, Zhu Minjia, Xiao Le, Zhao Zeqing, Bai Yuxing, Zhang Ke
Department of Orthodontics, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Beijing 100050, China.
School of Stomatology, Chongqing Medical University, Chongqing 401147, China.
Polymers (Basel). 2023 Jun 8;15(12):2611. doi: 10.3390/polym15122611.
Smart dental materials are designed to intelligently respond to physiological changes and local environmental stimuli to protect the teeth and promote oral health. Dental plaque, or biofilms, can substantially reduce the local pH, causing demineralization that can then progress to tooth caries. Progress has been made recently in developing smart dental materials that possess antibacterial and remineralizing capabilities in response to local oral pH in order to suppress caries, promote mineralization, and protect tooth structures. This article reviews cutting-edge research on smart dental materials, their novel microstructural and chemical designs, physical and biological properties, antibiofilm and remineralizing capabilities, and mechanisms of being smart to respond to pH. In addition, this article discusses exciting and new developments, methods to further improve the smart materials, and potential clinical applications.
智能牙科材料旨在智能地响应生理变化和局部环境刺激，以保护牙齿并促进口腔健康。牙菌斑或生物膜会大幅降低局部pH值，导致脱矿，进而发展为龋齿。最近在开发智能牙科材料方面取得了进展，这些材料具有响应局部口腔pH值的抗菌和再矿化能力，以抑制龋齿、促进矿化并保护牙齿结构。本文综述了智能牙科材料的前沿研究，包括其新颖的微观结构和化学设计、物理和生物学特性、抗生物膜和再矿化能力以及对pH值做出智能响应的机制。此外，本文还讨论了令人兴奋的新进展、进一步改进智能材料的方法以及潜在的临床应用。
