Department of Health Management Center & Institute of Health Management, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Chinese Academy of Sciences Sichuan Translational Medicine Research Hospital, Chengdu, Sichuan, China.
Front Endocrinol (Lausanne). 2023 Jun 19;14:1188487. doi: 10.3389/fendo.2023.1188487. eCollection 2023.
The association between () infection and metabolic syndrome (MetS) has been studied previously; however, the results remain controversial, which could be partly due to the different criteria used for defining MetS. We adopted five MetS criteria to provide better understanding of the association between infection and MetS.
Physical examination data of 100,708 subjects were obtained from January 2014 to December 2018. MetS was defined based on five criteria including: International Diabetes Federation (IDF), The Third Report of the National Cholesterol Education Program Expert Panel, Adult Treatment Panel III (ATP III), Joint Statement of International Multi-Societies (JIS), Chinese Diabetes Society (CDS), and the Guidelines for the Prevention and Treatment of Type 2 Diabetes in China (2017 edition)(CDS DM). Multivariate logistic regression analysis was performed to elucidate the association between infection and MetS and its components.
The prevalence of MetS defined assessed using IDF, ATP III, JIS, CDS and CDS DM criteria was 15.8%, 19.9%, 23.7%, 8.7% and 15.4%, respectively. In males, the prevalence of MetS assessed using the five criteria in -positive group was higher than that in negative-group; however, in females, same results were obtained using the three international criteria. In males, the prevalence of all MetS components was found to be higher in the -positive group than those in the negative group; however, in females, only the prevalence of dyslipidemia and waist circumferences exhibited significant differences. Multivariate logistic regression analysis revealed that infection in males was positively correlated with MetS. Additionally, infection was found to be positively correlated with the waist circumference in the general population, and with hypertension and hyperglycemia in males.
infection was found to be positively associated with MetS in males in China.
先前已经研究了 （）感染与代谢综合征（MetS）之间的关联；然而，结果仍存在争议，这可能部分归因于用于定义 MetS 的标准不同。我们采用了五种 MetS 标准，以更好地理解 感染与 MetS 之间的关联。
我们从 2014 年 1 月至 2018 年 12 月获得了 100708 名受试者的体检数据。根据国际糖尿病联合会（IDF）、美国国家胆固醇教育计划专家小组第三次报告（ATP III）、成人治疗专家组 III（ATP III）、联合多国学会声明（JIS）、中国糖尿病协会（CDS）和《中国 2 型糖尿病防治指南（2017 年版）》（CDS DM）这五个标准定义 MetS。采用多变量 logistic 回归分析阐明 感染与 MetS 及其各组分之间的关联。
使用 IDF、ATP III、JIS、CDS 和 CDS DM 标准评估的 MetS 患病率分别为 15.8%、19.9%、23.7%、8.7%和 15.4%。在男性中，-阳性组中使用五种标准评估的 MetS 患病率高于阴性组；然而，在女性中，使用三种国际标准也得到了相同的结果。在男性中，-阳性组的所有 MetS 组分的患病率均高于阴性组；然而，在女性中，只有血脂异常和腰围的患病率存在显著差异。多变量 logistic 回归分析表明，男性 感染与 MetS 呈正相关。此外，在一般人群中，感染与腰围呈正相关，在男性中与高血压和高血糖呈正相关。
在中国男性中，发现 感染与 MetS 呈正相关。
