Institute for Healthcare Management and Research, University Duisburg-Essen, Essen, Germany.
Department of Otorhinolaryngology, Head and Neck Surgery, Section of Rhinology and Allergy, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany.
Eur J Health Econ. 2024 Jun;25(4):579-600. doi: 10.1007/s10198-023-01598-3. Epub 2023 Jul 7.
Allergic rhinitis (AR) and allergic asthma (AA) are chronic respiratory diseases that represent a global health problem. One aim of this study was to analyze the Health-related Quality of Life (HRQoL) of the patients in order to identify statistically significant influencing factors that determine HRQoL. Another aim was to assess and analyze data on cost-of-illness from a statutory health insurance perspective.
The EQ-5D-5L was used to evaluate the patients' HRQoL. To identify the factors influencing the HRQoL, a multinomial logistic regression analysis was conducted using groups based on the EQ-5D-5L index value as dependent variable. Routine data were analyzed to determine total healthcare costs.
The average EQ-5D-5L index was 0.85 (SD 0.20). A high age, the amount of disease costs, low internal health-related control beliefs and high ozone exposure in the residential area were found to be statistically significant influencing factors for a low HRQoL, whereas low age, male sex and a good possibility to avoid the allergens were found to be statistically significant factors influencing a high HRQoL. On average, the study participants incurred annual costs of €3072 (SD: 3485), of which €699 (SD: 743) could be assigned to allergic respiratory diseases.
Overall, the patients in the VerSITA study showed a high level of HRQoL. The identified influencing factors can be used as starting points for improving the HRQoL of patients with allergic respiratory diseases. From the perspective of a statutory health insurance, per person expenditures for allergic respiratory diseases are rather low.
过敏性鼻炎(AR)和过敏性哮喘(AA)是两种慢性呼吸道疾病,它们是全球性的健康问题。本研究旨在分析患者的健康相关生活质量(HRQoL),以确定影响 HRQoL 的统计学显著因素。另一个目的是从法定健康保险的角度评估和分析疾病成本数据。
使用 EQ-5D-5L 评估患者的 HRQoL。为了确定影响 HRQoL 的因素,我们使用基于 EQ-5D-5L 指数值的分组作为因变量进行了多项逻辑回归分析。分析常规数据以确定总医疗保健费用。
平均 EQ-5D-5L 指数为 0.85(SD 0.20)。高年龄、疾病费用金额、内部健康相关控制信念水平低以及居住地区臭氧暴露水平高被发现是 HRQoL 较低的统计学显著影响因素,而低年龄、男性和避免过敏原的可能性高被发现是 HRQoL 较高的统计学显著影响因素。研究参与者的平均年度费用为 3072 欧元(SD:3485),其中 699 欧元(SD:743)可归因于过敏性呼吸道疾病。
总体而言,VerSITA 研究中的患者表现出较高的 HRQoL。确定的影响因素可以作为改善过敏性呼吸道疾病患者 HRQoL 的起点。从法定健康保险的角度来看,过敏性呼吸道疾病的人均支出相对较低。