健康年轻成年人样本中的饮酒与口腔微生物组组成。
Alcohol consumption and oral microbiome composition in a sample of healthy young adults.
机构信息
New York University Langone Health, New York, NY 10016, United States.
Department of Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, United States.
出版信息
Alcohol Alcohol. 2023 Nov 11;58(6):573-577. doi: 10.1093/alcalc/agad048.
Abstract
The oral microbiomes of 24 healthy adults (50% female; mean age = 24.3) were examined using 16 s ribosomal RNA sequencing and compared between light and heavy drinkers. Beta diversity was related at the trend level to drinking group, and light drinkers had significantly higher abundances of key oral taxa such as Lactobacillales. These preliminary results may offer insight into early effects of heavy drinking on the composition of the oral microbiome.
摘要
对 24 名健康成年人（50%为女性；平均年龄=24.3 岁）的口腔微生物组进行了 16S 核糖体 RNA 测序，并比较了轻饮者和重度饮者之间的差异。β多样性与饮酒组呈趋势相关，轻饮者的关键口腔分类群（如乳杆菌科）丰度显著更高。这些初步结果可能为深入了解重度饮酒对口腔微生物组组成的早期影响提供了线索。
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