Department of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, Students Campus, 6000 Stara Zagora, Bulgaria.
Toxins (Basel). 2023 Jul 19;15(7):464. doi: 10.3390/toxins15070464.
The subject of this review paper is to evaluate the underestimated hazard of multiple mycotoxin exposure of animals/humans for the appearance of foodborne ailments and diseases. The significance of joint mycotoxin interaction in the development of foodborne diseases is discussed, and appropriate conclusions are made. The importance of low feed/food levels of some target mycotoxins co-contaminations in food and feedstuffs for induction of target foodborne mycotoxicoses is also studied in the available literature. The appropriate hygiene control and the necessary risk assessment in regard to possible hazards for animals and humans are also discussed, and appropriate suggestions are made. Some internationally recognized prophylactic measures, management of the risk, and the necessity of elaboration of new international regulations in regard to the maximum permitted levels are also carefully discussed and analysed in the cases of multiple mycotoxin contaminations. The necessity of harmonization of mycotoxin regulations and control measures at international levels is also discussed in order to facilitate food trade between the countries and to ensure global food safety.
本文旨在评估动物/人类接触多种霉菌毒素的潜在危害，以了解其对食源性疾病的影响。文中探讨了霉菌毒素共同作用对食源性疾病发展的影响，并得出了相应的结论。此外，本文还研究了饲料/食品中某些目标霉菌毒素低水平混合污染对目标性霉菌毒素病的诱导作用。文中还讨论了针对动物和人类可能存在的危害进行适当卫生控制和风险评估的必要性，并提出了相应的建议。文中还详细讨论和分析了在多种霉菌毒素污染的情况下，国际上公认的预防措施、风险管理以及制定新的国际限量标准的必要性。为了促进国家间的食品贸易并确保全球食品安全，文中还讨论了在国际层面协调霉菌毒素法规和控制措施的必要性。
