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萝卜叶多糖的益生元和抗脂肪生成作用

Prebiotic and Anti-Adipogenic Effects of Radish Green Polysaccharide.

作者信息

Lee Yu Ra, Lee Hye-Bin, Kim Yoonsook, Shin Kwang-Soon, Park Ho-Young

机构信息

Food Functionality Research Division, Korea Food Research Institute, Wanju-gun 55365, Republic of Korea.

Department of Food Science and Biotechnology, Kyonggi University, Suwon 16227, Republic of Korea.

出版信息

Microorganisms. 2023 Jul 24;11(7):1862. doi: 10.3390/microorganisms11071862.

DOI:10.3390/microorganisms11071862
PMID:37513035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10385334/
Abstract

Radish ( L.) greens are consumed as a source of nutrition, and their polysaccharides such as rhamnogalacturonan-I possess certain beneficial properties. This study investigated the prebiotic effects of a radish green polysaccharide (RGP) on gut health and obesity. The prebiotic activity of RGP was evaluated based on the pH changes and short-chain fatty acids (SCFAs) concentration. The results showed that 0.5% RGP had a higher prebiotic activity score than inulin and increased SCFAs production in all five prebiotic strains. Moreover, RGP inhibited fat accumulation in 3T3-L1 adipocytes, indicating its potential to reduce obesity. Overall, these findings suggested that the polysaccharide of radish greens has prebiotic effects and may serve as a beneficial prebiotic for gut health and obesity.

摘要

萝卜(L.)叶作为一种营养来源被食用,其多糖如鼠李半乳糖醛酸聚糖-I具有一定的有益特性。本研究调查了萝卜叶多糖(RGP)对肠道健康和肥胖的益生元效应。基于pH变化和短链脂肪酸(SCFAs)浓度评估了RGP的益生元活性。结果表明,0.5%的RGP比菊粉具有更高的益生元活性评分,并增加了所有五种益生元菌株中SCFAs的产生。此外,RGP抑制了3T3-L1脂肪细胞中的脂肪积累,表明其具有减轻肥胖的潜力。总体而言,这些发现表明萝卜叶多糖具有益生元效应,可能作为一种有益的益生元促进肠道健康并减轻肥胖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/fa6e2e005e90/microorganisms-11-01862-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/f1671a44b444/microorganisms-11-01862-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/712595536123/microorganisms-11-01862-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/fa6e2e005e90/microorganisms-11-01862-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/f1671a44b444/microorganisms-11-01862-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/712595536123/microorganisms-11-01862-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef2/10385334/fa6e2e005e90/microorganisms-11-01862-g003.jpg

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A water soluble extract of radish greens ameliorates high fat diet-induced obesity in mice and inhibits adipogenesis in preadipocytes.
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Food Funct. 2022 Jul 18;13(14):7494-7506. doi: 10.1039/d1fo04152e.
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