心脏病中的线粒体功能障碍：.的潜在治疗作用

Cao Xinxin, Yao Fan, Zhang Bin, Sun Xiaobo

Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing, China.

Front Pharmacol. 2023 Jul 20;14:1218803. doi: 10.3389/fphar.2023.1218803. eCollection 2023.

Heart diseases have a high incidence and mortality rate, and seriously affect people's quality of life. Mitochondria provide energy for the heart to function properly. The process of various heart diseases is closely related to mitochondrial dysfunction. (), as a traditional Chinese medicine, is widely used to treat various cardiovascular diseases. Many studies have confirmed that and ginsenosides can regulate and improve mitochondrial dysfunction. Therefore, the role of mitochondria in various heart diseases and the protective effect of on heart diseases by regulating mitochondrial function were reviewed in this paper, aiming to gain new understanding of the mechanisms, and promote the clinical application of .

心脏病具有高发病率和死亡率，严重影响人们的生活质量。线粒体为心脏正常运作提供能量。各种心脏病的发病过程与线粒体功能障碍密切相关。（）作为一种传统中药，被广泛用于治疗各种心血管疾病。许多研究证实，（）和人参皂苷可以调节并改善线粒体功能障碍。因此，本文综述了线粒体在各种心脏病中的作用以及（）通过调节线粒体功能对心脏病的保护作用，旨在对其机制有新的认识，并促进（）的临床应用。