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可扩展的心血管生理信号和肢体健康实时监测集成系统。

Extensible Integrated System for Real-Time Monitoring of Cardiovascular Physiological Signals and Limb Health.

机构信息

State Key Laboratory for Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, Beijing, 100083, China.

Center of Materials Science and Optoelectronic Engineering, University of Chinese Academy of Sciences, Beijing, 100049, China.

出版信息

Adv Mater. 2023 Dec;35(51):e2304596. doi: 10.1002/adma.202304596. Epub 2023 Nov 13.

Abstract

In recent decades, the rapid growth in flexible materials, new manufacturing technologies, and wearable electronics design techniques has helped establish the foundations for noninvasive photoelectric sensing systems with shape-adaptability and "skin-like" properties. Physiological sensing includes humidity, mechanical, thermal, photoelectric, and other aspects. Photoplethysmography (PPG), an important noninvasive method for measuring pulse rate, blood pressure, and blood oxygen, uses the attenuated signal obtained by the light absorbed and reflected from living tissue to a light source to realize real-time monitoring of human health status. This work illustrates a patch-type optoelectronic system that integrates a flexible perovskite photodetector and all-inorganic light-emitting diodes (LEDs) to realize the real-time monitoring of human PPG signals. The pulse rate of the human body and the swelling degree of finger joints can be extracted and analyzed using photodetectors, thus monitoring human health for the prevention and early diagnosis of certain diseases. Specifically, this work develops a 3D wrinkled-serpentine interconnection wire that increases the shape adaptability of the device in practical applications. The PPG signal sensor reported in this study has considerable potential for future wearable intelligent medical applications.

摘要

近几十年来,柔性材料、新型制造技术和可穿戴电子设计技术的快速发展,为具有适应性和“类皮肤”特性的非侵入式光电传感系统奠定了基础。生理传感包括湿度、机械、热、光电等方面。光电容积脉搏波描记术(PPG)是一种重要的无创测量脉搏率、血压和血氧的方法,它利用光源从活体组织吸收和反射的光衰减信号来实现人体健康状况的实时监测。这项工作展示了一种贴片式光电系统,该系统集成了柔性钙钛矿光电探测器和全无机发光二极管(LED),以实现人体 PPG 信号的实时监测。通过光电探测器可以提取和分析人体的脉搏率和指关节肿胀程度,从而监测人体健康,预防和早期诊断某些疾病。具体来说,这项工作开发了一种 3D 褶皱蛇形互连线,提高了器件在实际应用中的形状适应性。本研究中报道的 PPG 信号传感器在未来的可穿戴智能医疗应用中具有相当大的潜力。

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