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解锁尿石症管理的新方法:营养保健品。

Unlocking New Approaches to Urolithiasis Management Nutraceuticals.

作者信息

Singh Ravindra Pal, Mishra Anurag, Chandel Shailendra Singh, Agarwal Mohit, Chawra Himmat Singh, Singh Mithilesh, Dubey Gaurav

机构信息

Department of Pharmacy, NIMS Institute of Pharmacy, NIMS University Rajasthan, Jaipur, India.

出版信息

Curr Pharm Biotechnol. 2024;25(9):1124-1131. doi: 10.2174/1389201024666230821122416.

Abstract

Urolithiasis, commonly known as kidney stones, is characterized by the formation of hard deposits in the urinary tract. These stones can cause severe pain and discomfort, and their management typically involves a combination of medical interventions and lifestyle modifications. According to the literature, 30% and 50% of urolithiasis cases recur. Between 9 and 12% of persons in industrialised countries are predicted to have urolithiasis at some time. Due to the high frequency of stone formation, recurrent nature, and prevalence in adults, it has a significant impact on society, the person, and the health care system. Adopting the best prophylactic measures is crucial in light of these developments to decrease the impact of urolithiasis on individuals and society. In recent years, there has been growing interest in the potential role of nutraceuticals in the management of urolithiasis. Nutraceuticals, such as herbal extracts, vitamins, minerals, and probiotics, have gained recognition for their potential in promoting urinary health and reducing the risk of urolithiasis. These compounds can aid in various ways, including inhibiting crystal formation, enhancing urine pH balance, reducing urinary calcium excretion, and supporting kidney function. Additionally, nutraceuticals can help alleviate symptoms associated with urolithiasis, such as pain and inflammation. While medical interventions remain crucial, incorporating nutraceuticals into a comprehensive management plan can offer a holistic approach to urolithiasis, improving patient outcomes and quality of life. Therefore, nutraceuticals may be a desirable choice for treating and avoiding recurring urolithiasis for patients and medical professionals. Therefore, the present study has focused on nutraceuticals' role in preventing urolithiasis.

摘要

尿石症,俗称肾结石,其特征是在尿路中形成坚硬的沉积物。这些结石会引起严重的疼痛和不适,其治疗通常需要结合医学干预和生活方式的改变。根据文献,30%至50%的尿石症病例会复发。预计工业化国家9%至12%的人在某个时候会患上尿石症。由于结石形成的高频率、复发性以及在成年人中的患病率,它对社会、个人和医疗保健系统都有重大影响。鉴于这些情况,采取最佳的预防措施对于减少尿石症对个人和社会的影响至关重要。近年来,人们对营养保健品在尿石症管理中的潜在作用越来越感兴趣。营养保健品,如草药提取物、维生素、矿物质和益生菌,因其在促进泌尿健康和降低尿石症风险方面的潜力而得到认可。这些化合物可以通过多种方式发挥作用,包括抑制晶体形成、增强尿液pH平衡、减少尿钙排泄以及支持肾功能。此外,营养保健品可以帮助缓解与尿石症相关的症状,如疼痛和炎症。虽然医学干预仍然至关重要,但将营养保健品纳入综合管理计划可以为尿石症提供一种整体的治疗方法,改善患者的治疗效果和生活质量。因此,营养保健品可能是患者和医疗专业人员治疗和避免复发性尿石症的理想选择。因此,本研究聚焦于营养保健品在预防尿石症中的作用。

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