Department of Technology of Cosmetic and Pharmaceutical Products, Medical College, University of Information Technology and Management in Rzeszow, Sucharskiego 2, 35-225 Rzeszow, Poland.
Department of Analytical Chemistry, Medical University of Lublin, Aleje Raclawickie 1, 20-059 Lublin, Poland.
Int J Mol Sci. 2023 Aug 26;24(17):13232. doi: 10.3390/ijms241713232.
Due to the high demand for products that can help treat various skin conditions, the interest in plant extracts, which are a valuable source of phytochemicals, is constantly growing. In this work, the properties of extracts and ferments from L. and their potential use in cosmetic products were compared. For this purpose, their composition, antioxidant properties and cytotoxicity against skin cells, keratinocytes and fibroblasts were assessed in vitro. In addition, the ability to inhibit the activity of collagenase and elastase was compared, which enabled the assessment of their potential to inhibit skin aging. Microbiological analyses carried out on different bacterial strains were made in order to compare their antibacterial properties. The conducted analyses showed that both dogwood extract and ferment have antioxidant and anti-aging properties. In addition, they can have a positive effect on the viability of keratinocytes and fibroblasts and inhibit the proliferation of various pathogenic bacteria, which indicates their great potential as ingredients in skin care preparations. The stronger activity of the ferment compared to the extract indicates the legitimacy of carrying out the fermentation process of plant raw materials using kombucha in order to obtain valuable products for the cosmetics industry.
由于人们对能够治疗各种皮肤状况的产品的需求很高，对植物提取物（植物化学物质的宝贵来源）的兴趣也在不断增长。在这项工作中，比较了 L. 的提取物和发酵物的特性及其在化妆品产品中的潜在用途。为此，在体外评估了它们的组成、抗氧化特性和对皮肤细胞、角质形成细胞和成纤维细胞的细胞毒性。此外，还比较了抑制胶原酶和弹性蛋白酶活性的能力，这使得评估它们抑制皮肤衰老的潜力成为可能。为了比较它们的抗菌特性，对不同的细菌菌株进行了微生物分析。进行的分析表明，山茱萸提取物和发酵物都具有抗氧化和抗衰老特性。此外，它们可以对角质形成细胞和成纤维细胞的活力产生积极影响，并抑制各种致病菌的增殖，这表明它们作为护肤品成分具有巨大的潜力。与提取物相比，发酵物的活性更强，这表明使用康普茶对植物原料进行发酵过程是合理的，以获得化妆品行业有价值的产品。
