Lin Shuqiong, Su Xia, Chen Liqun, Cai Zhiming
Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
Longyan First Affiliated Hospital of Fujian Medical University, Longyan, China.
Front Nutr. 2023 Aug 31;10:1215688. doi: 10.3389/fnut.2023.1215688. eCollection 2023.
Sarcopenia is a complication of asthma, and asthmatics with sarcopenia are at an increased risk of poor prognosis. Anti-inflammatory intervention promising as an effective measure to prevent sarcopenia among patients with asthma. Diet is an important way to regulate inflammation throughout the body. The dietary inflammatory index (DII) is an index that assesses an individual's overall dietary inflammatory potential. The relationship between DII and sarcopenia among patients with asthma is not clear.
To examine the correlation between DII and the sarcopenia among individuals with asthma.
The National Health and Nutrition Examination Survey (NHANES) was the data source utilized in this study, spanning two time periods from 1999 to 2006 and 2011 to 2018. The study encompassed 3,389 participants in total. DII was calculated using the results of the participants' 24-h dietary recall interviews. Patients were categorized into three groups based on the DII tertile: T1 group ( = 1,130), T2 group ( = 1,129), and T3 group ( = 1,130). Logistic regression analysis, taking into account the NHANES recommended weights, was performed to assess the relationship between DII and sarcopenia.
After full adjustment, there was a significant positive correlation between DII levels and the risk of sarcopenia in asthmatic patients (OR: 1.27, 95% CI: 1.13-1.42, < 0.001). Compared with T1 group, T3 group had higher risk of sarcopenia (T2: OR: 1.39, 95%CI: 0.88-2.18, = 0.157; T3: OR: 2.37, 95%CI: 1.47-3.83, < 0.001).
There was a significant positive correlation between DII and the risk of sarcopenia.
肌肉减少症是哮喘的一种并发症，患有肌肉减少症的哮喘患者预后不良的风险增加。抗炎干预有望成为预防哮喘患者肌肉减少症的有效措施。饮食是调节全身炎症的重要方式。饮食炎症指数（DII）是评估个体整体饮食炎症潜力的指标。哮喘患者中DII与肌肉减少症之间的关系尚不清楚。
探讨哮喘患者中DII与肌肉减少症之间的相关性。
本研究使用的数据源为美国国家健康与营养检查调查（NHANES），涵盖1999年至2006年以及2011年至2018年两个时间段。该研究共纳入3389名参与者。DII通过参与者24小时饮食回顾访谈的结果计算得出。患者根据DII三分位数分为三组：T1组（=1130）、T2组（=1129）和T3组（=1130）。进行逻辑回归分析，并考虑NHANES推荐权重，以评估DII与肌肉减少症之间的关系。
经过全面调整后，哮喘患者的DII水平与肌肉减少症风险之间存在显著正相关（OR：1.27，95%CI：1.13 - 1.42，<0.001）。与T1组相比，T3组患肌肉减少症的风险更高（T2：OR：1.39，95%CI：0.88 - 2.18，=0.157；T3：OR：2.37，95%CI：1.47 - 3.83，<0.001）。
DII与肌肉减少症风险之间存在显著正相关。
