Department of Global and Community Health, College of Public Health, George Mason University, Fairfax, Virginia, USA.
Environmental Health Sciences Department, Mailman School of Public Health, Columbia University, New York, New York, USA.
BJOG. 2024 Apr;131(5):655-664. doi: 10.1111/1471-0528.17668. Epub 2023 Sep 24.
From menarche until menopause, the average menstruator will use over 11 000 tampons or sanitary pads. Vaginal and vulvar tissue is highly permeable, and chemicals are absorbed without undergoing first-pass metabolism.
To conduct a review of the literature to determine exposure to environmental chemicals in menstrual products.
This review identified 15 papers over the past 10 years.
Papers that measured chemicals in menstrual products and that measured human biomarkers of chemical exposure were included. Papers had to also be available in English.
Reviewers assessed the articles and data provided. Multiple chemical groups were found.
Phthalates, volatile organic compounds, parabens, environmental phenols, fragrance chemicals, dioxins and dioxin-like compounds were detected in menstrual products. Research gaps were identified, including the lack of studies on newer products such as menstrual underwear and cups/discs. In addition to measuring chemicals in these products, future research should focus on clarifying the exposure per menstrual cycle to these chemicals to understand how menorrhagia and cycle length influence exposure from menstrual products.
Menstrual products contained measurable levels of a range of endocrine disrupting chemicals including phthalates, phenols and parabens. This reflects a potentially important route of exposure to chemicals that can impact women's reproductive health.
从初潮到绝经,平均每位女性在经期会使用超过 11000 个卫生棉条或卫生巾。阴道和外阴组织的渗透性很强,化学物质会被直接吸收,而不会经历首过代谢。
对文献进行综述,以确定女性在使用月经产品时接触到的环境化学物质。
在过去 10 年中,本综述共识别出 15 篇相关文献。
纳入测量月经产品中化学物质以及人体化学暴露生物标志物的文献。文献必须为英文文献。
评估人员对文章和提供的数据进行评估。研究发现了多种化学物质,包括邻苯二甲酸酯、挥发性有机化合物、对羟基苯甲酸酯、环境酚类、香料化学品、二恶英和类二恶英化合物。研究还发现了一些空白,例如缺乏对月经内衣、杯/盘等新产品的研究。未来的研究除了要测量这些产品中的化学物质,还应重点关注阐明每个月经周期内接触这些化学物质的情况,以了解月经过多和周期长度如何影响月经产品暴露。
月经产品中含有多种内分泌干扰化学物质,包括邻苯二甲酸酯、酚类和对羟基苯甲酸酯,这反映了女性接触这些可能影响生殖健康的化学物质的一个重要潜在途径。