Méndez-Lozano Néstor, Apatiga-Castro Miguel, Ruíz-Baltazar Alvaro de Jesús, Luz-Asunción Miguel de la, Pérez-Ramírez Eduardo E
Campus Querétaro, Universidad del Valle de México, Blvd. Juriquilla No. 1000 A Del., Santa Rosa Jáuregui 76230, Querétaro, Mexico.
CONAHCYT-Centro de Física Aplicada y Tecnología Avanzada, Universidad Nacional Autónoma de México, Boulevard Juriquilla 3001, Santiago de Querétaro 76230, Querétaro, Mexico.
J Funct Biomater. 2023 Sep 11;14(9):467. doi: 10.3390/jfb14090467.
The goal of this study is to evaluate the influence of the concentration of silver on the structural and antimicrobial in vitro properties of silver-doped hydroxyapatite powders obtained using the precipitation method. Different concentrations of silver were evaluated to assess the antimicrobial properties. X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, scanning electron microscopy (SEM), and dispersive energy spectroscopy (EDS) were used to characterize the powders. XRD and FTIR showed that the hydroxyapatite structure is not affected by the incorporation of silver; on the other hand, EDS showed the presence of silver in the powders. Antibacterial studies showed the efficiency of hydroxyapatite powders in inhibiting bacterial growth as silver concentration increases. According to the results, silver-doped hydroxyapatite powders are suggested for use in the prevention and treatment of infections in bone and dental tissues.
本研究的目的是评估银浓度对采用沉淀法制备的掺银羟基磷灰石粉末的结构和体外抗菌性能的影响。评估了不同浓度的银以测定抗菌性能。使用X射线衍射（XRD）、傅里叶变换红外光谱（FTIR）、拉曼光谱、扫描电子显微镜（SEM）和色散能谱（EDS）对粉末进行表征。XRD和FTIR表明，羟基磷灰石结构不受银掺入的影响；另一方面，EDS显示粉末中存在银。抗菌研究表明，随着银浓度的增加，羟基磷灰石粉末抑制细菌生长的效率提高。根据结果，建议将掺银羟基磷灰石粉末用于预防和治疗骨组织和牙组织感染。
