Tashmukhamedova M A, Almatov K T, Syrov V N, Sultanov M B, Abidov A A
Vopr Med Khim. 1986 Sep-Oct;32(5):24-8.
Oxidative phosphorylation and Ca2+-transport functions of liver mitochondria were normalized in rats with alloxane diabetes after peroral administration of phytoecdisteroids - ecdisterone and turkesterone (5 mg/kg) or nerobol (10 mg/kg) within 15 days. These drugs normalized the activity of NADH dehydrogenase and succinate dehydrogenase in respiratory chain of mitochondria, increased distinctly stability of the enzymes to the effect of such factors as heating, effect of phospholipase A2 or trypsin.
在15天内对四氧嘧啶糖尿病大鼠经口给予植物蜕皮甾酮——蜕皮甾酮和土克甾酮（5毫克/千克）或奈罗勃（10毫克/千克）后，肝脏线粒体的氧化磷酸化和钙转运功能恢复正常。这些药物使线粒体呼吸链中NADH脱氢酶和琥珀酸脱氢酶的活性恢复正常，显著提高了这些酶对诸如加热、磷脂酶A2或胰蛋白酶等因素作用的稳定性。
