Medical Records Department, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Operation Management Office, Affiliated Banan Hospital of Chongqing Medical University, Chongqing, China.
Immun Inflamm Dis. 2023 Sep;11(9):e1013. doi: 10.1002/iid3.1013.
Influenza-related encephalopathy is a rapidly progressive encephalopathy that usually presents during the early phase of influenza infection and primarily manifests as central nervous system dysfunction. This study aimed to analyze the current research status and hotspots of influenza-related encephalopathy since 2000 through bibliometrics analysis.
The Web of Science Core Collection (WOSCC) was used to extract global papers on influenza-related encephalopathy from 2000 to 2022. Meanwhile, the VOSviewer and CiteSpace software were used for data processing and result visualization.
A total of 561 published articles were included in the study. Japan was the country that published the most articles, with 205 articles, followed by the United States and China. Okayama University and Tokyo Medical University published the most articles, followed by Nagoya University, Tokyo University, and Juntendo University. Based on the analysis of keywords, four clusters with different research directions were identified: "Prevalence of H1N1 virus and the occurrence of neurological complications in different age groups," "mechanism of brain and central nervous system response after influenza virus infection," "various acute encephalopathy" and "diagnostic indicators of influenza-related encephalopathy."
The research progress, hotspots, and frontiers on influenza-related encephalopathy after 2000 were described through the visualization of bibliometrics. The findings will lay the groundwork for future studies and provide a reference for influenza-related encephalopathy. Research on influenza-related encephalopathy is basically at a stable stage, and the number of research results is related to outbreaks of the influenza virus.
流感相关性脑病是一种快速进展性脑病，通常在流感感染的早期阶段出现，主要表现为中枢神经系统功能障碍。本研究旨在通过文献计量学分析，分析 2000 年以来流感相关性脑病的研究现状和热点。
利用 Web of Science 核心合集（WOSCC）从 2000 年至 2022 年提取全球关于流感相关性脑病的论文。同时，使用 VOSviewer 和 CiteSpace 软件进行数据处理和结果可视化。
共纳入 561 篇发表的文章。日本发表的文章最多，为 205 篇，其次是美国和中国。发表文章最多的机构是冈山大学和东京医科大学，其次是名古屋大学、东京大学和顺天堂大学。基于关键词分析，确定了四个具有不同研究方向的聚类：“H1N1 病毒的流行和不同年龄组发生神经系统并发症”、“流感病毒感染后大脑和中枢神经系统反应的机制”、“各种急性脑病”和“流感相关性脑病的诊断指标”。
通过文献计量学的可视化描述了 2000 年后流感相关性脑病的研究进展、热点和前沿。研究结果将为未来的研究奠定基础，并为流感相关性脑病提供参考。流感相关性脑病的研究基本上处于稳定阶段，研究成果的数量与流感病毒的爆发有关。
