在碳正离子催化体系上嘧啶并[4,5-b]喹啉的多组分合成
Multicomponent synthesis of pyrimido[4,5-b] quinolines over a carbocationic catalytic system.
作者信息
Moosavi-Zare Ahmad Reza, Najafi Raha
机构信息
Department of Chemical Engineering, Hamedan University of Technology, Hamedan, 65155, Iran.
出版信息
Sci Rep. 2023 Oct 1;13(1):16501. doi: 10.1038/s41598-023-43793-5.
Abstract
Trityl chloride (TrCl) was efficiently used as a neutral catalyst for the multicomponent cyclization reaction of an aldehyde with dimedone and 6-amino-1,3-dimethyluracil for the preparation of pyrimido[4,5-b] quinolines in chloroform under reflux condition.
摘要
三氯甲基苯（TrCl）在回流条件下于氯仿中被有效地用作中性催化剂，用于醛与达米酮和6-氨基-1,3-二甲基尿嘧啶的多组分环化反应，以制备嘧啶并[4,5-b]喹啉。
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