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在碳正离子催化体系上嘧啶并[4,5-b]喹啉的多组分合成

Multicomponent synthesis of pyrimido[4,5-b] quinolines over a carbocationic catalytic system.

作者信息

Moosavi-Zare Ahmad Reza, Najafi Raha

机构信息

Department of Chemical Engineering, Hamedan University of Technology, Hamedan, 65155, Iran.

出版信息

Sci Rep. 2023 Oct 1;13(1):16501. doi: 10.1038/s41598-023-43793-5.

DOI:10.1038/s41598-023-43793-5
PMID:37779154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10543543/
Abstract

Trityl chloride (TrCl) was efficiently used as a neutral catalyst for the multicomponent cyclization reaction of an aldehyde with dimedone and 6-amino-1,3-dimethyluracil for the preparation of pyrimido[4,5-b] quinolines in chloroform under reflux condition.

摘要

三氯甲基苯（TrCl）在回流条件下于氯仿中被有效地用作中性催化剂，用于醛与达米酮和6-氨基-1,3-二甲基尿嘧啶的多组分环化反应，以制备嘧啶并[4,5-b]喹啉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/38d17f336ac5/41598_2023_43793_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/e5fc4e4c8492/41598_2023_43793_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/38fb67586019/41598_2023_43793_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/e26bd3d075bf/41598_2023_43793_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/38d17f336ac5/41598_2023_43793_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/e5fc4e4c8492/41598_2023_43793_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/38fb67586019/41598_2023_43793_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/e26bd3d075bf/41598_2023_43793_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fa3/10543543/38d17f336ac5/41598_2023_43793_Fig4_HTML.jpg

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