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锌在人类健康中的多功能作用:最新进展

Multifunctional role of zinc in human health: an update.

作者信息

Kiouri Despoina P, Tsoupra Evi, Peana Massimiliano, Perlepes Spyros P, Stefanidou Maria E, Chasapis Christos T

机构信息

Institute of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece.

Department of Chemistry, Laboratory of Organic Chemistry, National Kapodistrian University of Athens, 15772 Athens, Greece.

出版信息

EXCLI J. 2023 Aug 4;22:809-827. doi: 10.17179/excli2023-6335. eCollection 2023.

Abstract

Zinc is a multipurpose trace element for the human body, as it plays a crucial part in various physiological processes, such as cell growth and development, metabolism, cognitive, reproductive, and immune system function. Its significance in human health is widely acknowledged, and this has led the scientific community towards more research that aims to uncover all of its beneficial properties, especially when compared to other essential metal ions. One notable area where zinc has shown beneficial effects is in the prevention and treatment of various diseases, including cancer. This review aims to explain the involvement of zinc in specific health conditions such as cancer, coronavirus disease 2019 (COVID-19) and neurological disorders like Alzheimer's disease, as well as its impact on the gut microbiome.

摘要

锌是人体所需的一种多功能微量元素,因为它在各种生理过程中发挥着关键作用,如细胞生长与发育、新陈代谢、认知、生殖以及免疫系统功能。它对人类健康的重要性已得到广泛认可,这促使科学界开展更多研究,旨在揭示其所有有益特性,尤其是与其他必需金属离子相比时。锌已显示出有益作用的一个显著领域是在包括癌症在内的各种疾病的预防和治疗方面。本综述旨在解释锌在特定健康状况中的作用,如癌症、2019冠状病毒病(COVID-19)以及阿尔茨海默病等神经疾病,以及它对肠道微生物群的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e64/10539547/fee7d0fe74bc/EXCLI-22-809-t-001.jpg

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