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饮用红茶与癌症风险:一项前瞻性研究。

Black tea consumption and cancer risk: a prospective study.

作者信息

Heilbrun L K, Nomura A, Stemmermann G N

出版信息

Br J Cancer. 1986 Oct;54(4):677-83. doi: 10.1038/bjc.1986.226.

DOI:10.1038/bjc.1986.226
PMID:3778808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2001507/
Abstract

In a prospective cohort study, men of Japanese ancestry were clinically examined from 1965 to 1968. For 7,833 of these men, data on black tea consumption habits were recorded. Since 1965, newly diagnosed cancer incidence cases have been identified: 152 colon, 151 lung, 149 prostate, 136 stomach, 76 rectum, 57 bladder, 30 pancreas, 25 liver, 12 kidney and 163 at other (miscellaneous) sites. Compared to almost-never drinkers, men habitually drinking black tea more than once/day had an increased relative risk (RR) for rectal cancer (RR = 4.2). This positive association (P = 0.0007) could not be accounted for by age or alcohol intake. We also observed a weaker but significant negative association of black tea intake and prostate cancer incidence (P = 0.020). There were no significant associations between black tea consumption and cancer at any other site.

摘要

在一项前瞻性队列研究中,1965年至1968年对日本裔男性进行了临床检查。对其中7833名男性记录了红茶饮用习惯数据。自1965年以来,已确定了新诊断的癌症发病病例:152例结肠癌、151例肺癌、149例前列腺癌、136例胃癌、76例直肠癌、57例膀胱癌、30例胰腺癌、25例肝癌、12例肾癌以及163例其他(杂项)部位的癌症。与几乎从不饮茶者相比,每天饮用红茶超过一次的男性患直肠癌的相对风险(RR)增加(RR = 4.2)。这种正相关关系(P = 0.0007)无法用年龄或酒精摄入量来解释。我们还观察到红茶摄入量与前列腺癌发病率之间存在较弱但显著的负相关关系(P = 0.020)。红茶消费与其他任何部位的癌症之间均无显著关联。

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本文引用的文献

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The carcinogenic activity of tannic acid; liver tumours induced in rats by prolonged subcutaneous administration of tannic acid solutions.单宁酸的致癌活性;通过长期皮下注射单宁酸溶液在大鼠中诱导产生的肝肿瘤。
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