Wang Hsiuying
Institute of Statistics, National Yang Ming Chiao Tung University, Hsinchu 300093, Taiwan.
Polymers (Basel). 2023 Oct 5;15(19):3999. doi: 10.3390/polym15193999.
Collagen, the most abundant protein in our bodies, plays a crucial role in maintaining the structural integrity of various tissues and organs. Beyond its involvement in skin elasticity and joint health, emerging research suggests that collagen may significantly impact the treatment of complex diseases, particularly those associated with tissue damage and inflammation. The versatile functions of collagen, including skin regeneration, improving joint health, and increasing bone strength, make it potentially useful in treating different diseases. To the best of my knowledge, the strategy of using collagen to treat comorbid diseases has not been widely studied. This paper aims to explore the potential of collagen in treating comorbid diseases, including rheumatoid arthritis, osteoarthritis, osteoporosis, psoriatic arthritis, sarcopenia, gastroesophageal reflux, periodontitis, skin aging, and diabetes mellitus. Collagen-based therapies have shown promise in managing comorbidities due to their versatile properties. The multifaceted nature of collagen positions it as a promising candidate for treating complex diseases and addressing comorbid conditions. Its roles in wound healing, musculoskeletal disorders, cardiovascular health, and gastrointestinal conditions highlight the diverse therapeutic applications of collagen in the context of comorbidity management.
胶原蛋白是我们体内含量最丰富的蛋白质，在维持各种组织和器官的结构完整性方面发挥着关键作用。除了其在皮肤弹性和关节健康方面的作用外，新出现的研究表明，胶原蛋白可能对复杂疾病的治疗产生重大影响，特别是那些与组织损伤和炎症相关的疾病。胶原蛋白的多种功能，包括皮肤再生、改善关节健康和增强骨骼强度，使其在治疗不同疾病方面具有潜在用途。据我所知，使用胶原蛋白治疗合并症的策略尚未得到广泛研究。本文旨在探讨胶原蛋白在治疗合并症方面的潜力，包括类风湿性关节炎、骨关节炎、骨质疏松症、银屑病关节炎、肌肉减少症、胃食管反流、牙周炎、皮肤老化和糖尿病。基于胶原蛋白的疗法因其多功能特性在管理合并症方面已显示出前景。胶原蛋白的多面性使其成为治疗复杂疾病和解决合并症的有希望的候选者。它在伤口愈合、肌肉骨骼疾病、心血管健康和胃肠道疾病中的作用凸显了胶原蛋白在合并症管理背景下的多样治疗应用。
