School of Public Health, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, People's Republic of China.
People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, People's Republic of China.
BMJ Open. 2023 Oct 18;13(10):e072408. doi: 10.1136/bmjopen-2023-072408.
This study aimed to estimate the prevalence of hyperuricaemia (HUA) and investigate its risk factors in the general adult population of Ningxia Hui Autonomous Region (NHAR), China.
Cross-sectional study.
Survey of cardiovascular disorders and their related risk factors in NHAR, China.
10 803 permanent residents aged 18 and older.
HUA was defined as serum uric acid levels >420 µmol/L for men and >360 µmol/L for women.
The overall prevalence of HUA in NHAR adults was 19.81% (95% CI 19.06 to 20.57), with prevalence values of 24.91% (95% CI 23.70 to 26.14) in men and 15.58% (95% CI 14.66 to 16.53, p<0.001) in women. The prevalence of HUA was higher in urban residents than in rural residents (23.26% vs 17.02%, p<0.001). HUA prevalence was relatively high in individuals younger than 30 years for both men and women, then decreased with age, and began to increase at the age of 40 for women and 60 for men. Higher level of education, being overweight or obese, alcohol consumption, hypertension, diabetes, higher triglycerides, higher total cholesterol and poorer renal function were associated with an increased risk of HUA.
HUA prevalence is high among adults in NHAR. Young adults under 30 years and women over 50 years were identified as populations at high risk for HUA. Further attention ought to be placed to promoting healthy diets and implementing early interventions to manage dyslipidaemia, obesity and blood glucose level, as well as advocating for moderation of alcohol consumption.
本研究旨在评估宁夏回族自治区(NHAR)普通成年人群中高尿酸血症(HUA)的患病率,并探讨其危险因素。
横断面研究。
中国 NHAR 心血管疾病及其相关危险因素调查。
10803 名年龄在 18 岁及以上的常住居民。
HUA 定义为男性血清尿酸水平>420μmol/L,女性>360μmol/L。
NHAR 成年人 HUA 的总体患病率为 19.81%(95%CI 19.06 至 20.57),男性患病率为 24.91%(95%CI 23.70 至 26.14),女性患病率为 15.58%(95%CI 14.66 至 16.53,p<0.001)。城镇居民 HUA 患病率高于农村居民(23.26%比 17.02%,p<0.001)。男性和女性 30 岁以下人群 HUA 患病率较高,随后随年龄增长而降低,女性 50 岁、男性 60 岁时开始升高。较高的教育程度、超重或肥胖、饮酒、高血压、糖尿病、较高的甘油三酯、总胆固醇和较差的肾功能与 HUA 风险增加相关。
NHAR 成年人 HUA 患病率较高。30 岁以下的年轻成年人和 50 岁以上的女性是 HUA 高危人群。应进一步关注促进健康饮食,实施早期干预以控制血脂异常、肥胖和血糖水平,并倡导适度饮酒。