Centre for One Health, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, 141004, India.
Ecohealth. 2023 Sep;20(3):300-322. doi: 10.1007/s10393-023-01654-7. Epub 2023 Nov 21.
Zoonotic diseases have a significant impact on both human and animal health globally. The present study was planned to prioritize the zoonoses in Punjab state of India. To develop a zoonotic disease prioritization scoring system, a comprehensive approach has been taken, including literature review, key person interviews with animal health experts (n = 12) and medical professionals (n = 7), and nine focus group discussions (FGDs) with veterinary academicians, medical professionals, and field veterinary doctors. The scoring system comprises of seven major criteria, each assigned a weightage score (ws): prevalence/incidence of the disease (ws = 0.20), severity of illnesses in humans (ws = 0.18), epidemic potential (ws = 0.16), socio-economic burden (ws = 0.16), availability of effective control and prevention measures (ws = 0.15), inter-sectoral collaborations (ws = 0.1), and bioterrorism potential (ws = 0.05). The finalized scoring system, accompanied by a list of 15 selected zoonotic diseases, was implemented among a group of 23 professionals engaged in zoonoses research (n = 7), animal health (n = 10), and medical health (n = 6) to determine their prioritization. The zoonotic diseases prioritized for the Punjab (India) included, Brucellosis (0.70) > Rabies (0.69) > Anthrax (0.64) > Leptospirosis (0.62) = Toxoplasmosis (0.62) = Highly Pathogenic Avian Influenza (HPAI) (0.62) > Bovine tuberculosis (0.61) > Q fever (0.60) > Cysticercosis (0.59) > Listeriosis (0.58) > Crimean-Congo haemorrhagic fever (CCHF) (0.57) > Japanese encephalitis (0.56) = Echinococcosis (0.56) > Dermatophytosis (0.53) > and Scrub typhus (0.48), respectively. Higher priority is suggested for endemic zoonoses (e.g., brucellosis and rabies) as compared to those with epidemic potential (e.g., CCHF, HPAI etc.) in Punjab. Results of the current study will help in the development of targeted control and prevention strategies for zoonotic diseases in Punjab and other geographical regions facing similar challenges.
动物源性传染病对全球人类和动物的健康都有重大影响。本研究旨在确定印度旁遮普邦的动物源性传染病优先顺序。为了制定动物源性传染病优先排序评分系统，我们采用了综合方法，包括文献综述、与动物健康专家（n=12）和医学专业人员（n=7）的关键人物访谈，以及与兽医学者、医学专业人员和现场兽医的九次焦点小组讨论。该评分系统由七个主要标准组成，每个标准都分配了一个权重得分（ws）：疾病的流行/发病率（ws=0.20）、人类疾病的严重程度（ws=0.18）、流行潜力（ws=0.16）、社会经济负担（ws=0.16）、有效控制和预防措施的可及性（ws=0.15）、部门间合作（ws=0.1）和生物恐怖主义潜力（ws=0.05）。在从事动物源性传染病研究的 23 名专业人员（n=7）、动物健康（n=10）和医疗健康（n=6）中实施了最终确定的评分系统和 15 种选定的动物源性传染病清单，以确定其优先顺序。旁遮普邦（印度）优先考虑的动物源性传染病包括：布鲁氏菌病（0.70）>狂犬病（0.69）>炭疽（0.64）>钩端螺旋体病（0.62）=弓形虫病（0.62）=高致病性禽流感（HPAI）（0.62）>牛结核病（0.61）>Q 热（0.60）>囊虫病（0.59）>李斯特菌病（0.58）>克里米亚-刚果出血热（0.57）>日本脑炎（0.56）=包虫病（0.56）>皮肤真菌病（0.53）>恙虫病（0.48）。与具有流行潜力（如 CCHF、HPAI 等）的疾病相比，建议对地方性动物源性传染病（如布鲁氏菌病和狂犬病）给予更高的优先级。本研究的结果将有助于在旁遮普邦和其他面临类似挑战的地理区域制定有针对性的动物源性传染病控制和预防策略。
