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职业暴露结束后人体骨骼铅含量的降低。

Decrease of skeletal lead levels in man after end of occupational exposure.

作者信息

Christoffersson J O, Ahlgren L, Schütz A, Skerfving S, Mattsson S

出版信息

Arch Environ Health. 1986 Sep-Oct;41(5):312-8. doi: 10.1080/00039896.1986.9936703.

DOI:10.1080/00039896.1986.9936703
PMID:3800436
Abstract

Lead levels in finger bone were monitored using an in vivo X-ray fluorescence technique in retired lead workers. Eight subjects followed for 2-5 yr directly after end of exposure all displayed a decrease. Their average half-time was 7 (range 3-15) yr. In a second group of six persons, followed from year 7 to year 13 after finishing lead work, a decrease was seen in all but one. The average half-time for this group was 8 (range 2 infinity) yr. The mean value for both groups was 7 yr. The results show that there is a decrease of lead in bone after the end of exposure and that it is considerably faster than estimated earlier from various data on lead metabolism.

摘要

采用体内X射线荧光技术对退休铅作业工人的指骨铅含量进行了监测。8名受试者在接触结束后直接随访2至5年,所有人的铅含量均呈下降趋势。他们的平均半衰期为7年(范围为3至15年)。在第二组6人中,从结束铅作业后的第7年至第13年进行随访,除1人外,其他人的铅含量均有所下降。该组的平均半衰期为8年(范围为2至无穷大)。两组的平均值均为7年。结果表明,接触结束后骨内铅含量下降,且下降速度比根据早期各种铅代谢数据估计的要快得多。

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