Partnership to End Addiction, New York, NY, USA.
Zucker School of Medicine at Hofstra/Northwell, Feinstein Institutes for Medical Research, Manhasset, NY, USA.
Addiction. 2024 Mar;119(3):530-543. doi: 10.1111/add.16391. Epub 2023 Nov 27.
To test differential outcomes between three 6-month text-messaging interventions to reduce at-risk drinking in help-seeking adults.
A three-arm single-blind randomized controlled trial with 1-, 3-, 6- and 12-month follow-ups.
United States. A fully remote trial without human contact, with participants recruited primarily via social media outlets.
Seven hundred and twenty-three adults (mean = 39.9 years, standard deviation = 10.0; 62.5% female) seeking to reduce their drinking were allocated to 6 months of baseline 'tailored statically' messaging (TS; n = 240), 'tailored adaptive' messaging (TA; n = 239) or 'drink tracking' messaging (DT; n = 244).
TS consisted of daily text messages to reduce harmful drinking that were tailored to demographics and alcohol use. TA consisted of daily, tailored text messages that were also adapted based on goal achievement and proactive prompts. DT consisted of a weekly assessment for self-reported drinking over the past 7 days.
The primary outcome measure was weekly sum of standard drinks (SSD) at 6-month follow-up. Secondary outcome measures included drinks per drinking day (DDD), number of drinking days (NDD) per week and heavy drinking days (HDD) at 1-, 3-, 6- and 12-month follow-ups.
At 6 months, compared with DT, TA resulted in significant SSD reductions of 16.2 (from 28.7 to 12.5) drinks [adjusted risk ratio (aRR) = 0.80, 95% confidence interval (CI) = 0.71, 0.91] using intent-to-treat analysis. TA also resulted in significant improvements in DDD (aRR = 0.84; 95% CI = 0.77-0.92) and drinking days per week (b = -0.39; 95% CI = -0.67, -0.10), but not HDD compared with DT at 6 months. TA was not significantly different from TS at any time-point, except DDD at 6 months. All groups made improvements in SSD at 12-month follow-up compared with baseline with an average reduction of 12.9 drinks per week across groups.
Automated tailored mobile messaging interventions are scalable solutions that can reduce weekly alcohol consumption in remote help-seeking drinkers over time.
测试三种为期 6 个月的短信干预措施在减少寻求帮助的成年人高危饮酒方面的差异结果。
一项三臂单盲随机对照试验,具有 1、3、6 和 12 个月的随访。
美国。一项完全远程试验,无人员接触,参与者主要通过社交媒体渠道招募。
723 名成年人(平均年龄= 39.9 岁,标准差= 10.0;62.5%为女性)寻求减少饮酒量,他们被分配到 6 个月的基线“量身定制静态”消息(TS;n=240)、“量身定制自适应”消息(TA;n=239)或“饮酒追踪”消息(DT;n=244)。
TS 由每日向减少有害饮酒的目标发送短信组成,这些短信是根据人口统计学和饮酒情况量身定制的。TA 由每日的、量身定制的短信组成,也根据目标实现和主动提示进行调整。DT 由过去 7 天内自我报告的每周饮酒评估组成。
主要结局测量是 6 个月随访时每周标准饮料量(SSD)。次要结局测量包括每周饮酒量(DDD)、每周饮酒天数(NDD)和每月饮酒天数(HDD)。
与 DT 相比,在 6 个月时,TA 导致 SSD 显著减少 16.2(从 28.7 降至 12.5),这使用意向治疗分析得到了调整风险比(aRR)=0.80,95%置信区间(CI)=0.71, 0.91。TA 还导致 DDD(aRR=0.84;95%CI=0.77-0.92)和每周饮酒天数(b=-0.39;95%CI=-0.67, -0.10)的显著改善,但与 DT 相比,在 6 个月时 HDD 没有显著改善。TA 在任何时间点都与 TS 没有显著差异,除了 6 个月时的 DDD。与基线相比,所有组在 12 个月随访时的 SSD 都有所改善,平均每周减少 12.9 份饮料。
自动化的定制移动消息传递干预措施是可扩展的解决方案,可以随着时间的推移减少远程寻求帮助的饮酒者的每周饮酒量。