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机器人外骨骼在脑卒中偏瘫患者中的体现:REFLEX 膝关节外骨骼提供的辅助整合的实验研究。

Robotic exoskeleton embodiment in post-stroke hemiparetic patients: an experimental study about the integration of the assistance provided by the REFLEX knee exoskeleton.

机构信息

Electronic Tecnology Area, Rey Juan Carlos University, Madrid, Spain.

Facultad de Ciencias Experimentales, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Madrid, Spain.

出版信息

Sci Rep. 2023 Dec 21;13(1):22908. doi: 10.1038/s41598-023-50387-8.

DOI:10.1038/s41598-023-50387-8
PMID:38129592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10739721/
Abstract

Hemiparetic gait is the most common motor-disorder after stroke and, in spite of rehabilitation efforts, it is persistent in 50% of community dwelling stroke-survivors. Robotic exoskeletons have been proposed as assistive devices to support impaired joints. An example of these devices is the REFLEX knee exoskeleton, which assists the gait of hemiparetic subjects and whose action seems to be properly embodied by stroke survivors, who were able to adapt the motion of their non-assisted limbs and, therefore, reduce their compensation mechanisms. This paper presents an experimental validation carried out to deepen into the effects of REFLEX's assistance in hemiparetic subjects. Special attention was paid to the effect produced in the muscular activity as a metric to evaluate the embodiment of this technology. Significant differences were obtained at the subject level due to the assistance; however, the high dispersion of the measured outcomes avoided extracting global effects at the group level. These results highlight the need of individually tailoring the action of the robot to the individual needs of each patient to maximize the beneficial outcomes. Extra research effort should be done to elucidate the neural mechanisms involved in the embodiment of external devices by stroke survivors.

摘要

偏瘫步态是中风后最常见的运动障碍,尽管进行了康复治疗,但仍有 50%的社区居住中风幸存者存在这种障碍。机器人外骨骼已被提议作为辅助设备来支撑受损的关节。REFLEX 膝关节外骨骼就是这些设备的一个例子,它可以帮助偏瘫患者进行步态训练,而且中风幸存者似乎能够很好地适应这种外骨骼的运动,从而减少代偿机制。本文介绍了一项旨在深入研究 REFLEX 对偏瘫患者的辅助作用的实验验证。特别关注 REFLEX 辅助作用对肌肉活动的影响,将其作为评估这项技术体现程度的指标。由于辅助作用,在个体水平上得到了显著差异;然而,由于测量结果的高度分散性,避免了在组水平上得出总体效果。这些结果强调了需要根据每个患者的个体需求来调整机器人的动作,以最大限度地提高有益效果。应该进行更多的研究工作,阐明中风幸存者对外部设备体现的神经机制。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/11ca279179e2/41598_2023_50387_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/6c723d65cac0/41598_2023_50387_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/fb89695f7948/41598_2023_50387_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/09b07066667d/41598_2023_50387_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/0ae3a73b8af7/41598_2023_50387_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/f9b92191f6f9/41598_2023_50387_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/0f89ca87e62b/41598_2023_50387_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/752ab6a01aef/41598_2023_50387_Fig12_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6334/10739721/e37e5df6577a/41598_2023_50387_Fig13_HTML.jpg
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