Kirtschig Gudula, Kinberger Maria
Medbase Gesundheitszentrum, Unterer Graben 1, 8500, Frauenfeld, Schweiz.
Klinik für Dermatologie, Venerologie und Allergologie, Division of Evidence-Based Medicine (dEBM), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Deutschland.
Dermatologie (Heidelb). 2024 Jan;75(1):22-29. doi: 10.1007/s00105-023-05267-7. Epub 2023 Dec 22.
Lichen sclerosus (LS) and lichen planus (LP) are chronic inflammatory dermatoses of unknown aetiology. They pose the most important differential diagnoses of inflammatory dermatoses in the genital area. There is often a delay in diagnosing LS and LP and subsequently treatment is initiated late in the course of the disease, which will lead to scarring and a decreased quality of life. There is an increased risk of the development of malignancies in the genital area in both diseases; however, early and continuous treatment with potent topical steroids will decrease this risk.
硬化性苔藓(LS)和扁平苔藓(LP)是病因不明的慢性炎症性皮肤病。它们是生殖器部位炎症性皮肤病最重要的鉴别诊断。硬化性苔藓和扁平苔藓的诊断往往会延迟,随后在疾病进程后期才开始治疗,这将导致瘢痕形成和生活质量下降。这两种疾病在生殖器部位发生恶性肿瘤的风险均增加;然而,早期持续使用强效外用类固醇进行治疗将降低这种风险。