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使用集成分类器和Shaply可解释人工智能改进卵巢癌预测

Improved Prediction of Ovarian Cancer Using Ensemble Classifier and Shaply Explainable AI.

作者信息

Abuzinadah Nihal, Kumar Posa Sarath, Alarfaj Aisha Ahmed, Alabdulqader Ebtisam Abdullah, Umer Muhammad, Kim Tai-Hoon, Alsubai Shtwai, Ashraf Imran

机构信息

Faculty of Computer Science and Information Technology, King Abdulaziz University, P.O. Box 80200, Jeddah 21589, Saudi Arabia.

Department of Information Science, University of Arkansas at Little Rock, Little Rock, AR 72204, USA.

出版信息

Cancers (Basel). 2023 Dec 11;15(24):5793. doi: 10.3390/cancers15245793.

Abstract

The importance of detecting and preventing ovarian cancer is of utmost significance for women's overall health and wellness. Referred to as the "silent killer," ovarian cancer exhibits inconspicuous symptoms during its initial phases, posing a challenge for timely identification. Identification of ovarian cancer during its advanced stages significantly diminishes the likelihood of effective treatment and survival. Regular screenings, such as pelvic exams, ultrasound, and blood tests for specific biomarkers, are essential tools for detecting the disease in its early, more treatable stages. This research makes use of the Soochow University ovarian cancer dataset, containing 50 features for the accurate detection of ovarian cancer. The proposed predictive model makes use of a stacked ensemble model, merging the strengths of bagging and boosting classifiers, and aims to enhance predictive accuracy and reliability. This combination harnesses the benefits of variance reduction and improved generalization, contributing to superior ovarian cancer prediction outcomes. The proposed model gives 96.87% accuracy, which is currently the highest model result obtained on this dataset so far using all features. Moreover, the outcomes are elucidated utilizing the explainable artificial intelligence method referred to as SHAPly. The excellence of the suggested model is demonstrated through a comparison of its performance with that of other cutting-edge models.

摘要

检测和预防卵巢癌对于女性的整体健康至关重要。卵巢癌被称为“沉默的杀手”,在其早期阶段症状不明显,给及时识别带来挑战。在晚期发现卵巢癌会显著降低有效治疗和存活的可能性。定期筛查,如盆腔检查、超声检查以及针对特定生物标志物的血液检测,是在早期更可治疗阶段检测该疾病的重要手段。本研究使用了苏州大学卵巢癌数据集,该数据集包含50个用于准确检测卵巢癌的特征。所提出的预测模型利用了堆叠集成模型,融合了装袋和提升分类器的优势,旨在提高预测准确性和可靠性。这种组合利用了方差减少和改进泛化的优点,有助于获得更好的卵巢癌预测结果。所提出的模型准确率为96.87%,这是目前使用所有特征在该数据集上获得的最高模型结果。此外,利用称为SHAPly的可解释人工智能方法对结果进行了阐释。通过将其性能与其他前沿模型进行比较,证明了所建议模型的卓越性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a23a/10742117/9e16fde064e7/cancers-15-05793-g001.jpg

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