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对使用口服避孕药的母亲母乳喂养的儿童进行长期随访。

Long-term follow-up of children breast-fed by mothers using oral contraceptives.

作者信息

Nilsson S, Mellbin T, Hofvander Y, Sundelin C, Valentin J, Nygren K G

出版信息

Contraception. 1986 Nov;34(5):443-57. doi: 10.1016/0010-7824(86)90054-5.

Abstract

In a long-term follow-up study 48 breast-fed children, whose mothers had used oral contraceptives containing 50 micrograms of ethinylestradiol while lactating, were compared to a matched control group whose mothers had not used any hormonal contraceptives during lactation. In spite of a very large number of data collected from several different sources of information, no effect could be demonstrated of the ingested steroid, neither upon the panorama of diseases nor upon intellectual or psychological behaviour of the infants and children up to 8 years of age. The mothers who used oral contraceptives lactated a significantly shorter period of time than the controls, but no differences were found in weight gain and height increase in the children between cases and controls.

摘要

在一项长期随访研究中,将48名母乳喂养儿童与一个匹配的对照组进行了比较,这些母乳喂养儿童的母亲在哺乳期使用了含50微克炔雌醇的口服避孕药,而对照组儿童的母亲在哺乳期未使用任何激素避孕药。尽管从几个不同信息来源收集了大量数据,但未发现摄入的甾体激素对疾病情况以及8岁以下婴幼儿和儿童的智力或心理行为有任何影响。使用口服避孕药的母亲的哺乳期明显短于对照组,但病例组和对照组儿童的体重增加和身高增长没有差异。

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