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传统手术与氟化氩准分子激光角膜切削术的超微结构比较

Ultrastructural comparison of conventional surgical and argon fluoride excimer laser keratectomy.

作者信息

Kerr-Muir M G, Trokel S L, Marshall J, Rothery S

出版信息

Am J Ophthalmol. 1987 Mar 15;103(3 Pt 2):448-53. doi: 10.1016/s0002-9394(14)77769-4.

DOI:10.1016/s0002-9394(14)77769-4
PMID:3826261
Abstract

We used scanning electron microscopy to examine the structure of the surfaces created during keratectomy procedures carried out by conventional surgery and ablation by an excimer laser. The walls and the floor of the surgical site were rough with undulations greater than 10 micron in size, caused by broken lamellae and ruptured cells. In contrast, the surfaces produced by the excimer laser were smooth with perturbations of 1 micron or less and were sealed with a pseudomembrane. This smooth, sealed surface produced by the laser is probably responsible for the transparency of the healed cornea in contrast to the scarring produced when a conventional surgical keratotomy heals.

摘要

我们使用扫描电子显微镜来检查传统手术角膜切除术过程中以及准分子激光消融过程中所形成的表面结构。手术部位的壁和底部很粗糙,有大小超过10微米的起伏,这是由破碎的板层和破裂的细胞造成的。相比之下,准分子激光产生的表面很光滑,扰动在1微米或更小,并被一层假膜封闭。与传统手术角膜切开术愈合时产生的瘢痕形成对比,激光产生的这种光滑、封闭的表面可能是愈合角膜保持透明的原因。

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Int Ophthalmol. 1993 Apr;17(2):89-93. doi: 10.1007/BF00942781.
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Phototherapeutic keratectomy for bullous keratopathy.光治疗性角膜切除术治疗大泡性角膜病变。
Br J Ophthalmol. 1995 Apr;79(4):335-8. doi: 10.1136/bjo.79.4.335.
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Development of a system for excimer laser corneal surgery.准分子激光角膜手术系统的研发。
Trans Am Ophthalmol Soc. 1989;87:854-983.
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Long-term effect of erbium-YAG laser (2.9 microns) on the primate cornea.铒钇铝石榴石激光(2.9微米)对灵长类动物角膜的长期影响。
Int Ophthalmol. 1991 Jul;15(4):249-58. doi: 10.1007/BF00171027.
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