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准分子激光治疗角膜表面病变:一项实验室与临床研究。

Excimer laser treatment of corneal surface pathology: a laboratory and clinical study.

作者信息

Gartry D, Kerr Muir M, Marshall J

机构信息

St Thomas's Hospital, London.

出版信息

Br J Ophthalmol. 1991 May;75(5):258-69. doi: 10.1136/bjo.75.5.258.

DOI:10.1136/bjo.75.5.258
PMID:1817467
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1042351/
Abstract

The argon fluoride excimer laser emits radiation in the far ultraviolet part of the electromagnetic spectrum (193 nm). Each photon has high individual energy. Exposure of materials or tissues with peak absorption around 193 nm results in removal of surface layers (photoablation) with extremely high precision and minimal damage to non-irradiated areas. This precision is confirmed in a series of experiments on cadaver eyes and the treatment of 25 eyes with anterior corneal disease (follow-up 6 to 30 months). Multiple zone excimer laser superficial keratectomy is considered the treatment of choice for rough, painful corneal surfaces. All patients in this group were pain-free postoperatively. Where good visual potential exists, ablation of a single axial zone is recommended and results in improved visual acuity and reduction of glare. A hyperopic shift was noted in this group.

摘要

氟化氩准分子激光在电磁光谱的远紫外部分(193纳米)发射辐射。每个光子都具有较高的个体能量。用峰值吸收在193纳米左右的激光照射材料或组织,可极其精确地去除表层(光蚀),且对未照射区域的损伤最小。在一系列对尸体眼睛的实验以及对25只患有角膜前部疾病眼睛的治疗(随访6至30个月)中证实了这种精确性。多区准分子激光表层角膜切除术被认为是粗糙、疼痛角膜表面的首选治疗方法。该组所有患者术后均无疼痛。在存在良好视力潜力的情况下,建议对单个轴向区域进行光蚀,可提高视力并减少眩光。该组出现了远视性移位。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ed/1042351/a4798665947f/brjopthal00567-0007-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ed/1042351/5d8091bfd90a/brjopthal00567-0008-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01ed/1042351/8c33fed6fa30/brjopthal00567-0008-b.jpg
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本文引用的文献

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Endothelial damage after anterior radial keratotomy. An electron microscopic study of rabbit cornea.放射状角膜切开术后内皮损伤。兔角膜的电子显微镜研究。
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Excimer laser surgery of the cornea.
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光治疗性角膜切削术:三级眼科诊所的当前方法及变化趋势
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