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耐药性的抗生素 : 机制和临床意义。

Antibiotic Resistance of : Mechanisms and Clinical Implications.

机构信息

Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.

出版信息

J Korean Med Sci. 2024 Jan 29;39(4):e44. doi: 10.3346/jkms.2024.39.e44.

Abstract

is a pathogenic bacterium associated with various gastrointestinal diseases, including chronic gastritis, peptic ulcers, mucosa-associated lymphoid tissue lymphoma, and gastric cancer. The increasing rates of antibiotic resistance and the emergence of multidrug-resistant strains pose significant challenges to its treatment. This comprehensive review explores the mechanisms underlying the resistance of to commonly used antibiotics and the clinical implications of antibiotic resistance. Additionally, potential strategies for overcoming antibiotic resistance are discussed. These approaches aim to improve the treatment outcomes of infections while minimizing the development of antibiotic resistance. The continuous evolution of treatment perspectives and ongoing research in this field are crucial for effectively combating this challenging infection.

摘要

是一种与多种胃肠道疾病相关的致病菌,包括慢性胃炎、消化性溃疡、黏膜相关淋巴组织淋巴瘤和胃癌。抗生素耐药率的不断增加和多药耐药株的出现对其治疗构成了重大挑战。本综述探讨了 对常用抗生素产生耐药性的机制以及抗生素耐药性的临床意义。此外,还讨论了克服抗生素耐药性的潜在策略。这些方法旨在改善 感染的治疗效果,同时最大限度地减少抗生素耐药性的发展。不断发展的治疗观点和该领域的持续研究对于有效对抗这一具有挑战性的感染至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7459/10825452/9b723617c7a0/jkms-39-e44-g001.jpg

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