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一种基于氮掺杂碳点的双模式检测传感器,用于通过智能手机对铁(III)和抗坏血酸进行可视化检测。

A Dual-Mode Detection Sensor Based on Nitrogen-Doped Carbon Dots for Visual Detection of Fe(III) and Ascorbic Acid via a Smartphone.

作者信息

Kayani Kawan F, Abdullah Chalak Najat

机构信息

Department of Chemistry, College of Science, University of Sulaimani, Qliasan Street, Sulaimani City, Kurdistan Region, 46002, Iraq.

Department of Chemistry, College of Science, Charmo University, Peshawa Street, Chamchamal, Sulaimani City, 46023, Iraq.

出版信息

J Fluoresc. 2025 Feb;35(2):1125-1137. doi: 10.1007/s10895-024-03604-0. Epub 2024 Feb 1.


DOI:10.1007/s10895-024-03604-0
PMID:38300485
Abstract

Accurately and promptly detecting Fe and ascorbic acid (AA) is a crucial objective. In this study, nitrogen-doped carbon dots (N-CDs) were synthesized using a one-step hydrothermal synthesis method with 6,9-diamino-2-ethoxyacridine lactate as the precursor. The introduction of Fe and AA resulted in both fluorescence (FL) quenching and enhancement of the synthesized N-CDs. The fluorescent response of the N-CDs probe to Fe was observed in the concentration range of 5-20 µM and 25-50 µM, with a limit of detection (LOD) of 290 nM. Remarkably, the fluorescence of the N-CDs was recovered upon the addition of AA to the N-CDs-Fe system. Using the "off-on" fluorescent N-CDs probe, a linear range of 40-90 µM was achieved with an LOD of 0.69 µM. Additionally, the feasibility of employing a smartphone equipped with an RGB Color Picker was demonstrated for the analysis of Fe and AA concentrations, providing a novel visual detection method. Furthermore, the application of N-CDs in solution demonstrated considerable potential for visually detecting Fe and AA. The proposed dual-mode detection sensor was found to be simple, efficient, and stable, enabling the successful determination of Fe and AA in practical samples with satisfactory results.

摘要

准确、及时地检测铁和抗坏血酸(AA)是一个关键目标。在本研究中,以6,9-二氨基-2-乙氧基吖啶乳酸为前驱体,采用一步水热合成法合成了氮掺杂碳点(N-CDs)。铁和抗坏血酸的引入导致合成的N-CDs荧光(FL)猝灭和增强。在5-20μM和25-50μM的浓度范围内观察到N-CDs探针对铁的荧光响应,检测限(LOD)为290 nM。值得注意的是,在N-CDs-Fe体系中加入抗坏血酸后,N-CDs的荧光恢复。使用“关-开”荧光N-CDs探针,线性范围为40-90μM,LOD为0.69μM。此外,还证明了使用配备RGB颜色选择器的智能手机分析铁和抗坏血酸浓度的可行性,提供了一种新颖的视觉检测方法。此外,N-CDs在溶液中的应用在视觉检测铁和抗坏血酸方面显示出巨大潜力。所提出的双模式检测传感器简单、高效且稳定,能够成功测定实际样品中的铁和抗坏血酸,结果令人满意。

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本文引用的文献

[1]
One-step synthesis of green emission carbon dots for selective and sensitive detection of nitrite ions and cellular imaging application.

RSC Adv. 2020-3-9

[2]
Rational design of MoS QDs and Eu as a ratiometric fluorescent probe for point-of-care visual quantitative detection of tetracycline via smartphone-based portable platform.

Anal Chim Acta. 2022-3-15

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Analyst. 2021-5-4

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Preparation of highly crystalline nitrogen-doped carbon dots and their application in sequential fluorescent detection of Fe and ascorbic acid.

Food Chem. 2020-4-27

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Sens Actuators B Chem. 2014-12-1

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Anal Bioanal Chem. 2020-5

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J Fluoresc. 2020-1

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Biomater Sci. 2019-6-6

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Nanoscale. 2018-5-3

[10]
Red-Emissive Carbon Dots for Fingerprints Detection by Spray Method: Coffee Ring Effect and Unquenched Fluorescence in Drying Process.

ACS Appl Mater Interfaces. 2017-5-24

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