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孟加拉国诺阿卡利地区肉类和家禽消费中重金属对健康的影响。

Health effects of heavy metals in meat and poultry consumption in Noakhali, Bangladesh.

作者信息

Chowdhury Akibul Islam, Alam Mohammad Rahanur

机构信息

Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Noakhali, Bangladesh.

Department of Nutrition and Food Engineering, Daffodil International University, Dhaka, Bangladesh.

出版信息

Toxicol Rep. 2024 Jan 17;12:168-177. doi: 10.1016/j.toxrep.2024.01.008. eCollection 2024 Jun.

Abstract

This study examined the quantities of heavy metals (Cd, Cr, Pb, Ni, Fe, and Cu) in commercially available meat, poultry, and game products in Noakhali, Bangladesh, and their potential health effects, as heavy metal contamination poses a significant food safety risk to human health Atomic Absorption Spectrophotometry was used to analyze heavy metals, and the health risk assessment was based on Estimated Daily Intake (EDI), Targeted Hazard Quotient (THQ), Total THQ, and Total Carcinogenic Risk (TCR). Most samples exceeded Maximum Allowable Concentrations (MAC) for heavy metals. The EDI value of Cd, Pb, and Cr for duck liver, goat liver, and pigeon brain, were higher than the Maximum Tolerable Dietary Intake (MTDI). Children had 1.28 times higher HI values than an adult. The calculation of THQ of all elements in adults and children was in the order of Cu; Pb; Ni; Cr; Cd; and Fe. The calculated TTHQ values were in the range of 0.051 to 1.988 and 0.047 to 3.975 for adults and children, respectively. The TCR values for Cd in poultry liver, brain, and meat, Sonali chicken, cow, pigeon, duck, and goat liver were higher than the reference value for adults and children, suggesting a potential cancer risk. The average exposure to lead leads to an increase in blood pressure by 0.47 mmHg and a decrease in IQ score by 1.94 points. The present study reveals the need to determine strong relationships between heavy metal exposure and food supply.

摘要

本研究检测了孟加拉国诺阿卡利市市售肉类、禽类和野味产品中的重金属(镉、铬、铅、镍、铁和铜)含量及其潜在健康影响,因为重金属污染对人类健康构成了重大食品安全风险。采用原子吸收分光光度法分析重金属,并基于估计每日摄入量(EDI)、目标危害商(THQ)、总THQ和总致癌风险(TCR)进行健康风险评估。大多数样品的重金属含量超过了最大允许浓度(MAC)。鸭肝、羊肝和鸽脑的镉、铅和铬的EDI值高于最大可耐受膳食摄入量(MTDI)。儿童的健康指数(HI)值比成年人高1.28倍。成人和儿童所有元素的THQ计算顺序为铜;铅;镍;铬;镉;和铁。成人和儿童计算出的总THQ值分别在0.051至1.988和0.047至3.975范围内。家禽肝脏、大脑和肉类、索纳利鸡、牛、鸽、鸭和羊肝脏中的镉的TCR值高于成人和儿童的参考值,表明存在潜在的癌症风险。平均铅暴露会导致血压升高0.47 mmHg,智商得分降低1.94分。本研究表明有必要确定重金属暴露与食物供应之间的紧密关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea5a/10832487/a10775e2d880/ga1.jpg

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