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用于生物应用的金属嵌入二氧化硅纳米颗粒的最新研究

Recent Studies on Metal-Embedded Silica Nanoparticles for Biological Applications.

作者信息

Cho Hye-Seong, Noh Mi Suk, Kim Yoon-Hee, Namgung Jayoung, Yoo Kwanghee, Shin Min-Sup, Yang Cho-Hee, Kim Young Jun, Yu Seung-Ju, Chang Hyejin, Rho Won Yeop, Jun Bong-Hyun

机构信息

Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea.

Bio & Medical Research Center, Bio Business Division, Korea Testing Certification, Gunpo 15809, Gyeonggi-do, Republic of Korea.

出版信息

Nanomaterials (Basel). 2024 Jan 26;14(3):268. doi: 10.3390/nano14030268.

DOI:10.3390/nano14030268
PMID:38334538
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10856399/
Abstract

Recently, silica nanoparticles (NPs) have attracted considerable attention as biocompatible and stable templates for embedding noble metals. Noble-metal-embedded silica NPs utilize the exceptional optical properties of novel metals while overcoming the limitations of individual novel metal NPs. In addition, the structure of metal-embedded silica NPs decorated with small metal NPs around the silica core results in strong signal enhancement in localized surface plasmon resonance and surface-enhanced Raman scattering. This review summarizes recent studies on metal-embedded silica NPs, focusing on their unique designs and applications. The characteristics of the metal-embedded silica NPs depend on the type and structure of the embedded metals. Based on this progress, metal-embedded silica NPs are currently utilized in various spectroscopic applications, serving as nanozymes, detection and imaging probes, drug carriers, photothermal inducers, and bioactivation molecule screening identifiers. Owing to their versatile roles, metal-embedded silica NPs are expected to be applied in various fields, such as biology and medicine, in the future.

摘要

近年来，二氧化硅纳米颗粒（NPs）作为用于嵌入贵金属的生物相容性和稳定模板受到了广泛关注。嵌入贵金属的二氧化硅NPs利用了新型金属的卓越光学特性，同时克服了单个新型金属NPs的局限性。此外，在二氧化硅核周围装饰有小金属NPs的金属嵌入二氧化硅NPs结构，会导致局部表面等离子体共振和表面增强拉曼散射中的强信号增强。本综述总结了关于金属嵌入二氧化硅NPs的近期研究，重点关注其独特设计和应用。金属嵌入二氧化硅NPs的特性取决于嵌入金属的类型和结构。基于这一进展，金属嵌入二氧化硅NPs目前被用于各种光谱应用中，用作纳米酶、检测和成像探针、药物载体、光热诱导剂和生物激活分子筛选标识符。由于其多功能作用，预计金属嵌入二氧化硅NPs未来将应用于生物学和医学等各个领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/c7e1e0e2ee26/nanomaterials-14-00268-g011.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/ceb052339755/nanomaterials-14-00268-g006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/c3778d93d2ed/nanomaterials-14-00268-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/5bb052c9d5b2/nanomaterials-14-00268-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/98621bbc5dc2/nanomaterials-14-00268-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/b6df9e728732/nanomaterials-14-00268-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/808bbb7f0b22/nanomaterials-14-00268-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/b7de8e90434a/nanomaterials-14-00268-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/90dc297c7a61/nanomaterials-14-00268-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c71/10856399/c7e1e0e2ee26/nanomaterials-14-00268-g011.jpg

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