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Base editing effectively prevents early-onset severe cardiomyopathy in Mybpc3 mutant mice.

作者信息

Wu Shuo, Yang Ping, Geng Zilong, Li Yige, Guo Zhizhao, Lou Yingmei, Zhang Shasha, Xiong Junhao, Hu Huan, Guo Xiaoling, Pu William T, Zhang Yan, Zhu Dan, Zhang Bing

机构信息

Key Laboratory of Systems Biomedicine, Shanghai Center for Systems Biomedicine, Department of Cardiovascular Surgery, Shanghai Chest Hospital, Engineering Research Center of Techniques and Instruments for Diagnosis and Treatment of Congenital Heart Disease, Institute of Developmental and Regenerative Medicine, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Basic Medical Research Center, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

出版信息

Cell Res. 2024 Apr;34(4):327-330. doi: 10.1038/s41422-024-00930-7. Epub 2024 Feb 9.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aef/10978934/c34ab253ef55/41422_2024_930_Fig1_HTML.jpg

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