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基于高效神经网络(EfficientNet)的组织病理学图像口腔鳞状细胞癌检测

Oral squamous cell carcinoma detection using EfficientNet on histopathological images.

作者信息

Albalawi Eid, Thakur Arastu, Ramakrishna Mahesh Thyluru, Bhatia Khan Surbhi, SankaraNarayanan Suresh, Almarri Badar, Hadi Theyazn Hassn

机构信息

Department of Computer Science, College of Computer Science and Information Technology, King Faisal University, Al-Ahsa, Saudi Arabia.

Department of Computer Science and Engineering, Faculty of Engineering and Technology, JAIN (Deemed-to-be University), Bangalore, India.

出版信息

Front Med (Lausanne). 2024 Jan 29;10:1349336. doi: 10.3389/fmed.2023.1349336. eCollection 2023.

Abstract

INTRODUCTION

Oral Squamous Cell Carcinoma (OSCC) poses a significant challenge in oncology due to the absence of precise diagnostic tools, leading to delays in identifying the condition. Current diagnostic methods for OSCC have limitations in accuracy and efficiency, highlighting the need for more reliable approaches. This study aims to explore the discriminative potential of histopathological images of oral epithelium and OSCC. By utilizing a database containing 1224 images from 230 patients, captured at varying magnifications and publicly available, a customized deep learning model based on EfficientNetB3 was developed. The model's objective was to differentiate between normal epithelium and OSCC tissues by employing advanced techniques such as data augmentation, regularization, and optimization.

METHODS

The research utilized a histopathological imaging database for Oral Cancer analysis, incorporating 1224 images from 230 patients. These images, taken at various magnifications, formed the basis for training a specialized deep learning model built upon the EfficientNetB3 architecture. The model underwent training to distinguish between normal epithelium and OSCC tissues, employing sophisticated methodologies including data augmentation, regularization techniques, and optimization strategies.

RESULTS

The customized deep learning model achieved significant success, showcasing a remarkable 99% accuracy when tested on the dataset. This high accuracy underscores the model's efficacy in effectively discerning between normal epithelium and OSCC tissues. Furthermore, the model exhibited impressive precision, recall, and F1-score metrics, reinforcing its potential as a robust diagnostic tool for OSCC.

DISCUSSION

This research demonstrates the promising potential of employing deep learning models to address the diagnostic challenges associated with OSCC. The model's ability to achieve a 99% accuracy rate on the test dataset signifies a considerable leap forward in earlier and more accurate detection of OSCC. Leveraging advanced techniques in machine learning, such as data augmentation and optimization, has shown promising results in improving patient outcomes through timely and precise identification of OSCC.

摘要

引言

口腔鳞状细胞癌(OSCC)在肿瘤学中是一个重大挑战,因为缺乏精确的诊断工具,导致病情识别延迟。目前OSCC的诊断方法在准确性和效率方面存在局限性,这凸显了对更可靠方法的需求。本研究旨在探索口腔上皮组织和OSCC组织病理图像的鉴别潜力。通过利用一个包含来自230名患者的1224张不同放大倍数且公开可用的图像的数据库,开发了一种基于EfficientNetB3的定制深度学习模型。该模型的目标是通过采用数据增强、正则化和优化等先进技术来区分正常上皮组织和OSCC组织。

方法

该研究利用一个用于口腔癌分析的组织病理成像数据库,其中包含来自230名患者的1224张图像。这些在不同放大倍数下拍摄的图像构成了训练基于EfficientNetB3架构构建的专门深度学习模型的基础。该模型接受训练以区分正常上皮组织和OSCC组织,采用了包括数据增强、正则化技术和优化策略在内的复杂方法。

结果

定制的深度学习模型取得了显著成功,在数据集上进行测试时显示出高达99%的准确率。如此高的准确率突出了该模型在有效区分正常上皮组织和OSCC组织方面的功效。此外,该模型还展现出令人印象深刻的精确率、召回率和F1分数指标,增强了其作为OSCC强大诊断工具的潜力。

讨论

本研究证明了采用深度学习模型应对与OSCC相关诊断挑战的巨大潜力。该模型在测试数据集上达到99%准确率的能力标志着在更早、更准确地检测OSCC方面取得了重大进展。利用机器学习中的先进技术,如数据增强和优化,已显示出通过及时、精确地识别OSCC来改善患者预后的有希望的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f09/10859441/63e7e7918a31/fmed-10-1349336-g001.jpg

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